A new method for the preparation of 1,3-dilithiopropyne: an efficient synthesis of homopropargyl alcohols

dc.creatorCabezas Pizarro, Jorge A.
dc.creatorPereira, Albán R. 
dc.creatorAmey, Adam R.
dc.date.accessioned2023-01-02T16:45:05Z
dc.date.accessioned2023-03-13T12:56:56Z
dc.date.available2023-01-02T16:45:05Z
dc.date.available2023-03-13T12:56:56Z
dc.date.created2023-01-02T16:45:05Z
dc.date.issued2001
dc.identifierhttps://www.sciencedirect.com/science/article/pii/S0040403901014290
dc.identifier0040-4039
dc.identifierhttps://hdl.handle.net/10669/87962
dc.identifier10.1016/S0040-4039(01)01429-0
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/6119281
dc.description.abstractControlled dilithiation of propargyl bromide with two equivalents of n-butyllithium, in the presence of TMEDA, produces the operational equivalent of the dianion 1,3-dilithiopropyne. The latter reacts efficiently with aldehydes and ketones to produce homopropargyl alcohols in a single step route and in high yields. Controlled dilithiation of propargyl bromide with n-BuLi, in the presence of TMEDA, produces the operational equivalent of the dianion 1,3-dilithiopropyne. The latter reacts efficiently with aldehydes and ketones to produce homopropargyl alcohols in a single step route in high yields.
dc.languageeng
dc.sourceTetrahedron Letters, 42(39), p. 6819-6822.
dc.subjectCHEMICAL ANALYSIS
dc.subjectCHEMICAL PROCESSES
dc.subjectCHEMISTRY
dc.subjectCHEMICAL ELEMENTS
dc.titleA new method for the preparation of 1,3-dilithiopropyne: an efficient synthesis of homopropargyl alcohols
dc.typeartículo científico


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