Synthesis and Antibacterial Activity of Aromatic Homopropargyl Alcohols

dc.creatorUmaña, Christian A.
dc.creatorArias Echandi, María Laura
dc.creatorCabezas Pizarro, Jorge A.
dc.date.accessioned2023-01-03T16:38:56Z
dc.date.accessioned2023-03-13T12:47:33Z
dc.date.available2023-01-03T16:38:56Z
dc.date.available2023-03-13T12:47:33Z
dc.date.created2023-01-03T16:38:56Z
dc.date.issued2017
dc.identifierhttps://www.scirp.org/journal/paperinformation.aspx?paperid=79145
dc.identifier2161-4687
dc.identifierhttps://hdl.handle.net/10669/87986
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/6118858
dc.description.abstractSeveral aromatic homopropargyl alcohols, and derivatives were prepared by one-pot reaction of 1,3-dilithiopropyne (or its equivalent) with aldehydes and ketones. The antibacterial activity, of alcohols thus prepared, against Gram (+) and Gram (−) bacteria was tested. This activity varies depending upon substitution on the homopropargyl alcohol unit. Apparently, the benzene ring and the free hydroxyl group (or its alcoxide) are needed, in the homopropar- gyl alcohol unit, to be biologically active.
dc.languageeng
dc.sourceInternational Journal of Organic Chemistry, 2017, 7, 295-300.
dc.subjectHomopropargyl Alcohols
dc.subject1,3-Dilithiopropyne
dc.subjectAntibacterial Activity
dc.titleSynthesis and Antibacterial Activity of Aromatic Homopropargyl Alcohols
dc.typeartículo científico


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