dc.contributor | Universidade Estadual Paulista (UNESP) | |
dc.date.accessioned | 2022-05-01T11:23:34Z | |
dc.date.accessioned | 2022-12-20T03:45:56Z | |
dc.date.available | 2022-05-01T11:23:34Z | |
dc.date.available | 2022-12-20T03:45:56Z | |
dc.date.created | 2022-05-01T11:23:34Z | |
dc.date.issued | 2021-01-01 | |
dc.identifier | Sao Paulo Medical Journal, v. 139, n. 6, p. 545-555, 2021. | |
dc.identifier | 1516-3180 | |
dc.identifier | http://hdl.handle.net/11449/233890 | |
dc.identifier | 10.1590/1516-3180.2020.0799.R1.0904221 | |
dc.identifier | 2-s2.0-85121032818 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/5413989 | |
dc.description.abstract | BACKGROUND: Despite the several options available for supplements containing vitamins C and E, evidence regarding the prevalence of deficiency or insufficiency of these vitamins is weak. OBJECTIVES: To estimate the prevalence of deficiency or insufficiency of vitamins C and E and associated factors among women of childbearing age, in Brazil. DESIGN AND SETTING: Systematic review and meta-analysis conducted at a Brazilian public university. METHODS: A search from index inception until May 2020 was conducted. Meta-analyses were performed using inverse variance for fixed models, with summary proportions calculation using Freeman-Tukey dou-ble arcsine (base case). Reporting and methodological quality were assessed using the Joanna Briggs Institute tool for prevalence studies. RESULTS: Our review identified 12 studies, comprising 1,316 participants, especially breastfeeding wom-en. There was at least one quality weakness in all studies, mainly regarding sampling method (i.e. conve-nience sampling) and small sample size. The prevalence of vitamin C deficiency ranged from 0% to 40%. Only vitamin E deficiency was synthetized in meta-analyses, with mean prevalences of 6% regardless of the alpha-tocopherol cutoff in plasma, and 5% and 16% for cutoffs of <1.6-12.0 mmol/l and < 16.2 mmol/l, respectively. The cumulative meta-analysis suggested that a trend to lower prevalence of vitamin E deficiency occurred in recent studies. CONCLUSIONS: Although the studies identified in this systematic review had poor methodological and reporting quality, mild-moderate vitamin C and E deficiencies were identified, especially in breastfeeding women. Thus, designing and implementing policies does not seem to be a priority, because the need has not been properly dimensioned among women of childbearing age in Brazil. REGISTRATION NUMBER IN PROSPERO: CRD42020221605. | |
dc.language | eng | |
dc.relation | Sao Paulo Medical Journal | |
dc.source | Scopus | |
dc.subject | Hypovitaminosis | |
dc.subject | Lactating | |
dc.subject | Maternal nutrition | |
dc.subject | Nutritional epidemiology | |
dc.title | Deficiency of vitamins C and E in women of childbearing age in Brazil: A systematic review and meta-analysis | |
dc.type | Artículos de revistas | |