Effects of fluoride intake on insulin sensitivity and insulin signal transduction

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-28T20:48:16Z
dc.date.accessioned2022-12-20T02:01:15Z
dc.date.available2022-04-28T20:48:16Z
dc.date.available2022-12-20T02:01:15Z
dc.date.created2022-04-28T20:48:16Z
dc.date.issued2008-10-01
dc.identifierFluoride, v. 41, n. 4, p. 270-275, 2008.
dc.identifier0015-4725
dc.identifierhttp://hdl.handle.net/11449/225400
dc.identifier2-s2.0-58849133027
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5405530
dc.description.abstractForty seven-week-old male castrated Wistar rats were randomly divided evenly into a control group and a fluoride (F) group. The latter was given a single dose of NaF from a solution containing 1.0 mg F ion/kg bw, administered by gavage. After 30 min, the following experiments were performed: intravenous insulin tolerance test (0.75 U/kg bw) and determination of the insulin receptor substrate (pp 185-IRS-1/IRS/2) tyrosine phosphorylation status. The acute treatment with NaF promoted increased blood glycemia, but there were no significant changes in the insulin sensitivity and in the pp185 tyrosine phosphorylation status in the muscular or in the white adipose tissues. Copyright © 2008 The International Society for Fluoride Research Inc.
dc.languageeng
dc.relationFluoride
dc.sourceScopus
dc.subjectInsulin receptor substrate
dc.subjectInsulin sensitivity
dc.subjectInsulin signal
dc.subjectPlasma fluoride
dc.subjectRats and insulin
dc.titleEffects of fluoride intake on insulin sensitivity and insulin signal transduction
dc.typeActas de congresos


Este ítem pertenece a la siguiente institución