dc.contributorUniversidade Estadual de Campinas (UNICAMP)
dc.contributorUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-28T19:54:20Z
dc.date.accessioned2022-12-20T01:44:23Z
dc.date.available2022-04-28T19:54:20Z
dc.date.available2022-12-20T01:44:23Z
dc.date.created2022-04-28T19:54:20Z
dc.date.issued1996-01-01
dc.identifierCanadian Journal of Physiology and Pharmacology, v. 74, n. 6, p. 663-669, 1996.
dc.identifier0008-4212
dc.identifierhttp://hdl.handle.net/11449/224019
dc.identifier10.1139/y96-050
dc.identifier2-s2.0-0029821291
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5404148
dc.description.abstractIn this article we compare how sensitivity to the chronotropic effect of noradrenaline and adrenaline of right atria isolated from female rats is modified after repeated swimming or foot-shock stress, under the influence of the estrous cycle. Right atria from stressed female rats sacrificed at diestrus were subsensitive to both catecholamines, irrespective of the stresser agent. However, although subsensitivity to noradrenaline was of similar intensity, subsensitivity to adrenaline was more pronounced in right atria from foot shock stressed rats as opposed to swimming-stressed rats. Identical stress protocols did not induce any alteration in atrial sensitivity to catecholamines when the stressed female rats were sacrificed at estrus. We conclude that the stress reaction concerning the mediation of cardiac chronotropism by catecholamines is related to the severity of the stresser agent and is strongly influenced by the estrous cycle.
dc.languageeng
dc.relationCanadian Journal of Physiology and Pharmacology
dc.sourceScopus
dc.subjectAdrenaline
dc.subjectDiestrus
dc.subjectEstrus
dc.subjectFemale rats
dc.subjectFoot-shock stress
dc.subjectNoradrenaline
dc.subjectSwimming stress
dc.titleStress-induced subsensitivity to catecholamines depends on the estrous cycle
dc.typeArtículos de revistas


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