dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2021-06-26T06:17:39Z
dc.date.accessioned2022-12-19T23:08:54Z
dc.date.available2021-06-26T06:17:39Z
dc.date.available2022-12-19T23:08:54Z
dc.date.created2021-06-26T06:17:39Z
dc.date.issued2021-04-28
dc.identifierJournal Of Orthopaedic Surgery And Research. London: Bmc, v. 16, n. 1, 8 p., 2021.
dc.identifier1749-799X
dc.identifierhttp://hdl.handle.net/11449/210773
dc.identifier10.1186/s13018-021-02437-y
dc.identifierWOS:000645234300001
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5391375
dc.description.abstractBackground Platelet-rich plasma (PRP) has been used to favor anterior cruciate ligament (ACL) healing after reconstruction surgeries. However, clinical data are still inconclusive and subjective about PRP. Thus, we propose a quantitative method to demonstrate that PRP produced morphological structure changes. Methods Thirty-four patients undergoing ACL reconstruction surgery were evaluated and divided into control group (sixteen patients) without PRP application and experiment group (eighteen patients) with intraoperative application of PRP. Magnetic resonance imaging (MRI) scans were performed 3 months after surgery. We used Matlab (R) and machine learning (ML) in Orange Canvas (R) to texture analysis (TA) features extraction. Experienced radiologists delimited the regions of interest (RoIs) in the T2-weighted images. Sixty-two texture parameters were extracted, including gray-level co-occurrence matrix and gray level run length. We used the algorithms logistic regression (LR), naive Bayes (NB), and stochastic gradient descent (SGD). Results The accuracy of the classification with NB, LR, and SGD was 83.3%, 75%, 75%, respectively. For the area under the curve, NB, LR, and SGD presented values of 91.7%, 94.4%, 75%, respectively. In clinical evaluations, the groups show similar responses in terms of improvement in pain and increase in the IKDC index (International Knee Documentation Committee) and Lysholm score indices differing only in the assessment of flexion, which presents a significant difference for the group treated with PRP. Conclusions Here, we demonstrated quantitatively that patients who received PRP presented texture changes when compared to the control group. Thus, our findings suggest that PRP interferes with morphological parameters of the ACL.
dc.languageeng
dc.publisherBmc
dc.relationJournal Of Orthopaedic Surgery And Research
dc.sourceWeb of Science
dc.subjectKnee joint
dc.subjectClassification
dc.subjectMagnetic resonance imaging
dc.subjectTexture analysis
dc.subjectMachine learning
dc.subjectPlatelet-rich plasma
dc.titleTexture analysis to differentiate anterior cruciate ligament in patients after surgery with platelet-rich plasma
dc.typeArtículos de revistas


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