dc.contributorFed Univ Tocantins
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2021-06-25T12:39:38Z
dc.date.accessioned2022-12-19T23:00:40Z
dc.date.available2021-06-25T12:39:38Z
dc.date.available2022-12-19T23:00:40Z
dc.date.created2021-06-25T12:39:38Z
dc.date.issued2021-02-18
dc.identifierNatural Product Research. Abingdon: Taylor & Francis Ltd, 4 p., 2021.
dc.identifier1478-6419
dc.identifierhttp://hdl.handle.net/11449/210098
dc.identifier10.1080/14786419.2021.1892098
dc.identifierWOS:000625764100001
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5390695
dc.description.abstractEndophytic fungi are biodiverse and alternative source of bioactive compounds, due their different abilities of genetic expression and alteration of biosynthetic pathway when submitted to different culture conditions. The metabolic profile of three different crude extracts (A, B and C), obtained from the endophytic fungus Asordaria conoidea, were evaluated by HPLC and H-1 NMR. Antioxidant and allelochemical activity were also evaluated. OSMAC diversified the metabolic production, mainly in the solid culture, where the tyrosol, 4-hydroxybenzaldehyde, 2-phenylacetamide and vanillic acid were isolated. The structures of the compounds were elucidated mainly by NMR. Extracts had antioxidant potential, however, only Extract C showed allelochemical activity, as inhibition of 65.5% in growth. This study confirms the efficiency of the OSMAC platform in producing extracts of different properties and compounds. Herein the A. conoidea was isolated for the first time as an endophytic microorganism.
dc.languageeng
dc.publisherTaylor & Francis Ltd
dc.relationNatural Product Research
dc.sourceWeb of Science
dc.subjectEndophytic fungus
dc.subjectfungi metabolism
dc.subjectCochlospermum regium
dc.subjectallelochemical activity
dc.subjectaromatic compounds
dc.titleAromatic compounds from the endophytic fungus Asordaria conoidea and their allelochemical property using OSMAC strategy
dc.typeArtículos de revistas


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