Effects of muscular strength training and growth hormone (GH) supplementation on femoral bone tissue: analysis by Raman spectroscopy, dual-energy X-ray absorptiometry, and mechanical resistance
dc.contributor | Universidade Estadual de Campinas (UNICAMP) | |
dc.contributor | Universidade do Oeste Paulista – UNOESTE | |
dc.contributor | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2019-10-06T16:37:46Z | |
dc.date.accessioned | 2022-12-19T18:53:44Z | |
dc.date.available | 2019-10-06T16:37:46Z | |
dc.date.available | 2022-12-19T18:53:44Z | |
dc.date.created | 2019-10-06T16:37:46Z | |
dc.date.issued | 2019-01-01 | |
dc.identifier | Lasers in Medical Science. | |
dc.identifier | 1435-604X | |
dc.identifier | 0268-8921 | |
dc.identifier | http://hdl.handle.net/11449/189348 | |
dc.identifier | 10.1007/s10103-019-02821-5 | |
dc.identifier | 2-s2.0-85068162315 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/5370386 | |
dc.description.abstract | The aim of the present study was to verify the effects of muscular strength training and growth hormone (GH) supplementation on femoral bone tissue by Raman spectroscopy (Raman), dual-energy X-ray absorptiometry (DXA), and mechanical resistance (F-max) analysis. A total of 40 male Wistar animals, 60 days old, were used. The animals were distributed into four groups: control (C), control with GH (GHC), muscular strength training (T), and muscular strength training with GH (GHT). Blood samples were collected for the quantification of creatine kinase (CK-MB) and the femurs were removed for analysis by Raman, DXA, and F-max. A more pronounced increase in the bone mineral components was verified in the T group, for all the variables obtained by the Raman (calcium, phosphate, amide, and collagen). In addition, for animals submitted to GH supplementation, there was a reduction in the variable bone mineral density (BMD) obtained by the DXA (p < 0.05). Finally, the animals that received GH supplementation presented a higher F-max, but without statistical significance (p > 0.05). It was concluded that animals that received GH supplementation demonstrated a decrease in BMD. In addition, T alone was able to promote increased calcium, phosphate, amide, and collagen compounds in bone tissue. | |
dc.language | eng | |
dc.relation | Lasers in Medical Science | |
dc.rights | Acesso aberto | |
dc.source | Scopus | |
dc.subject | Anabolics | |
dc.subject | Bone tissue | |
dc.subject | Growth hormone | |
dc.subject | Muscular strength | |
dc.subject | Physical training | |
dc.title | Effects of muscular strength training and growth hormone (GH) supplementation on femoral bone tissue: analysis by Raman spectroscopy, dual-energy X-ray absorptiometry, and mechanical resistance | |
dc.type | Artículos de revistas |