Analysis of the effects of simvastatin on the mevalonate pathway, cell wall integrity and bacterial metabolome: evidence of the antimicrobial mechanism of action

dc.contributorTorres Cortês de Sousa, Iago
dc.creatorSousa, Iago Torres Cortês de
dc.creatorSilva, Kátia de Pádua
dc.creatorMüller, Karina Cogo
dc.date.accessioned2022-12-16T13:22:41Z
dc.date.available2022-12-16T13:22:41Z
dc.identifierhttps://doi.org/10.25824/redu/TJVOA2
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5363145
dc.descriptionThese data are the result of research carried out to investigate the antimicrobial action mechanism of simvastatin against S. aureus. Analyzes were performed to verify changes in gene expression, cell wall integrity, metabolome, proteome and HMG-CoA-reductase II enzyme.
dc.languageEnglish
dc.publisherRepositório de Dados de Pesquisa da Unicamp
dc.subjectChemistry
dc.subjectMedicine, Health and Life Sciences
dc.subjectSimavastatin
dc.subjectStaphylococcus aureus
dc.subjectDrug repositioning
dc.subjectAntibacterial agents
dc.subjectGene expression
dc.titleAnalysis of the effects of simvastatin on the mevalonate pathway, cell wall integrity and bacterial metabolome: evidence of the antimicrobial mechanism of action


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