Analysis of Strategies for Preventing and Controlling the Chikungunya Virus

Análisis de estrategias para prevenir y controlar el virus Chikunguña;
Análise de estratégias para prevenir e controlar o vírus Chikungunya

dc.creatorOlarte Garciá, Julián Alejandro
dc.creatorMuñoz Loaiza, Anibal
dc.date2021-03-19
dc.date.accessioned2022-12-15T18:17:30Z
dc.date.available2022-12-15T18:17:30Z
dc.identifierhttps://revistas.unimilitar.edu.co/index.php/rfcb/article/view/4341
dc.identifier10.18359/rfcb.4341
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5356255
dc.descriptionAlternatives to stop chikungunya outbreaks are oriented to vector control and developing a specific treatment and a preventive vaccine. Environmental control and mosquito bite prevention are undoubtedly essential to decrease the disease burden, but Aedes vectors continue to expand geographically and re-emerge. So, vaccination is proposed to respond to this etiology and recognized as a pressing need for affected countries. A mathematical host-vector model, including asymptomatic population, vector control, and vaccination (assuming the existence of a safe protective vaccine against the chikungunya virus), is suggested to analyze the effects of these efforts. Poisson distribution is applied to interpret the basic reproduction number. Then vaccination and vector control thresholds are established to prescribe the most effective protection measures against exposure to the chikungunya virus. In conclusion, it is advisable to continue with integrated control to reduce the economic impact of relevant public health responses and mitigate other infections since Aedes is a transmitter of other arboviruses such as dengue, Zika, and Mayaro. Furthermore, vaccinating all individuals in a community could be a costly and gradual process.en-US
dc.descriptionLas alternativas para detener los brotes de Chikunguña están orientadas, primero, al control del vector y, segundo, al desarrollo de un tratamiento específico y una vacuna preventiva. Es indudable la importancia del control ambiental y la prevención de la picadura de mosquitos para disminuir la carga de la enfermedad, pero sus vectores Aedes continúan expandiéndose geográficamente y resurgiendo, por lo que la vacunación se plantea como la respuesta a esta etiología y se reconoce como una necesidad prioritaria para los países afectados. Con el fin de analizar los efectos de los esfuerzos antes mencionados, se propone un modelo matemático hospedero-vector que incluye población asintomática, control de vectores y vacunación (se supone la existencia de una vacuna segura y protectora contra el virus Chikunguña). Se aplica el proceso de Poisson en epidemiología para interpretar el número básico de reproducción, y luego se establecen umbrales de vacunación y control vectorial que prescriben las medidas más efectivas para proteger contra la exposición al virus Chikunguña. Se concluye que para reducir el impacto económico de las respuestas de salud pública correspondientes es recomendable continuar con el control integrado, ya que Aedes es transmisor de otros arbovirus como dengue, Zika y Mayaro, lo que ayudaría también a la mitigación de estas otras infecciones. Además, proporcionar la vacuna a todos los individuos de una comunidad podría ser un proceso paulatino y costoso.es-ES
dc.descriptionAs alternativas para deter os surtos de chikungunya estão orientadas, em primeiro lugar, ao controle do vetor e, em segundo, ao desenvolvimento de um tratamento específico e de uma vacina. São inegáveis a importância do controle ambiental e a prevenção da picada de mosquitos para diminuir a carga da doença, mas seus vetores Aedes continuam se expandindo geograficamente e ressurgindo, razão pela qual a vacinação se apresenta como resposta a essa etiologia e se reconhece como necessidade prioritária para os países afetados. A fim de analisar os efeitos dos esforços antes mencionados, é proposto um modelo matemático hospedeiro-vetor que inclui população assintomática, controle de vetores e vacinação (é suposta a existência de uma vacina segura e protetora contra o vírus chikungunya). É aplicado o processo de Poisson em epidemiologia para interpretar o número básico de reprodução e logo estabelecidos os parâmetros para a vacinação e o controle vetorial que as medidas mais efetivas prescrevem para proteger da exposição ao vírus chikungunya. Conclui-se que, para reduzir o impacto econômico das respostas de saúde pública correspondentes, é recomendável continuar o controle integrado, já que Aedes é transmissor de outros arbovírus como dengue, zika e mayaro, o que ajudaria também para mitigar essas outras infecções. Além disso, proporcionar a vacina a todos os indivíduos de uma comunidade poderia ser um processo paulatino e caro.pt-BR
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dc.languageeng
dc.publisherUniversidad Militar Nueva Granadaes-ES
dc.relationhttps://revistas.unimilitar.edu.co/index.php/rfcb/article/view/4341/4719
dc.relationhttps://revistas.unimilitar.edu.co/index.php/rfcb/article/view/4341/4736
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dc.rightsDerechos de autor 2021 Revista Facultad de Ciencias Básicases-ES
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0es-ES
dc.sourceRevista Facultad de Ciencias Básicas; Vol. 16 No. 1 (2020); 57-68en-US
dc.sourceRevista Facultad de Ciencias Básicas; Vol. 16 Núm. 1 (2020); 57-68es-ES
dc.source2500-5316
dc.source1900-4699
dc.subjectCHIKVen-US
dc.subjectAedesen-US
dc.subjectVaccinationen-US
dc.subjectMosquito Controlen-US
dc.subjectMathematical modelen-US
dc.subjectBasic reproduction numberen-US
dc.subjectCHIKVes-ES
dc.subjectAedeses-ES
dc.subjectVacunaciónes-ES
dc.subjectControl del mosquitoes-ES
dc.subjectModelo matemáticoes-ES
dc.subjectNúmero reproductivo básicoes-ES
dc.subjectCHIKVpt-BR
dc.subjectAedespt-BR
dc.subjectVacinaçãopt-BR
dc.subjectControle do mosquitopt-BR
dc.subjectModelo matemáticpt-BR
dc.subjectNúmero reprodutivo básicopt-BR
dc.titleAnalysis of Strategies for Preventing and Controlling the Chikungunya Virusen-US
dc.titleAnálisis de estrategias para prevenir y controlar el virus Chikunguñaes-ES
dc.titleAnálise de estratégias para prevenir e controlar o vírus Chikungunyapt-BR
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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