Veterinary perspective of the renal system in sepsis

Perspectiva veterinaria del sistema renal en la sepsis

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dc.date2021-04-12
dc.date.accessioned2022-12-15T14:43:26Z
dc.date.available2022-12-15T14:43:26Z
dc.identifierhttps://revistamvz.unicordoba.edu.co/article/view/e2007
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5353411
dc.descriptionThis paper aims to review, discuss and define the factors associated with development of kidney injury in patients with sepsis, diagnosis alternatives, therapy and prevention, offering to the veterinarians an updated guide to improve the prognosis of sepsis patients. Sepsis is a clinical condition that leads to systemic complications and to multiple organ dysfunction syndrome (MODS), mainly due to poor tissue perfusion in humans and animals. Acute kidney injury (AKI) is considered the most frequent and lethal among organ complications secondary to sepsis, however the etiology of AKI in patients with sepsis is complex and multifactorial and not completely elucidated. Early diagnosis of AKI is difficult and consequently the treatment is not very successful, due to hemodynamic aspects. The ultrasonography seems to be a promising exam for early diagnosis of this lesion, especially with the advent of contrast-enhanced ultrasonography (CEUS) technique, which makes possible to detect microcirculation changes in the renal parenchyma, opening the door for a variety of physiological, clinical and therapeutic applications, however, studies proving CEUS accuracy for early detection of renal damage related to sepsis in humans and animals are still necessary.en-US
dc.descriptionEsta revisión tiene como objetivo discutir y definir los factores asociados con el desarrollo de lesión renal en pacientes con sepsis, alternativas de diagnóstico, terapia y prevención, ofreciendo a los veterinarios una guía actualizada para mejorar el pronóstico de los pacientes con sepsis. La sepsis es una condición clínica que conduce a complicaciones sistémicas y al síndrome de disfunción multiorgánica (MODS), principalmente debido a una pobre perfusión tisular en humanos y animales. La lesión renal aguda (LRA) se considera la más frecuente y letal entre las complicaciones orgánicas secundarias a la sepsis, sin embargo, la etiología de la LRA en pacientes con sepsis es compleja, multifactorial y no está completamente elucidada. El diagnóstico temprano de LRA es difícil y, en consecuencia, el tratamiento no es muy exitoso debido a los aspectos hemodinámicos. La ecografía parece ser un examen prometedor para el diagnóstico precoz de esta lesión, especialmente con el advenimiento de la técnica de ecografía contrastada (CEUS), que permite detectar cambios en la microcirculación de el parénquima renal, abriendo la puerta a una variedad de componentes fisiopatológicos, aplicaciones clínicas y terapéuticas, sin embargo, los estudios que demuestran la precisión de CEUS para la detección temprana de daño renal relacionado con sepsis en humanos y animales aún son limitados.es-ES
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dc.languagespa
dc.languageeng
dc.publisherUniversidad de Córdobaes-ES
dc.relationhttps://revistamvz.unicordoba.edu.co/article/view/e2007/2968
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dc.rightsDerechos de autor 2021 Beatriz Gasser, Ricardo Andres Ramirez-Uscategui, Marjury Cristina Maronezi, Ana Paula Rodrigues-Simões, Luiz Fernando Perez-Gomes, Letícia Pavan, Marcus Antonio Rossi-Felicianoes-ES
dc.sourceJournal MVZ Cordoba; Vol. 26 No. 2 (2021): Revista MVZ Córdoba Volumen 26(2) Mayo-Agosto 2021; e2007en-US
dc.sourceRevista MVZ Córdoba; Vol. 26 Núm. 2 (2021): Revista MVZ Córdoba Volumen 26(2) Mayo-Agosto 2021; e2007es-ES
dc.source1909-0544
dc.source0122-0268
dc.source10.21897/rmvz.v26.n2.2021
dc.subjectAcute kidney injuryen-US
dc.subjectinfectionen-US
dc.subjectinflammationen-US
dc.subjectmultiple organ failureen-US
dc.subjectperfusionen-US
dc.subjectrenal blood flowen-US
dc.subjectFlujo sanguíneo renales-ES
dc.subjectinfecciónes-ES
dc.subjectinflamaciónes-ES
dc.subjectinsuficiencia multiorgánicaes-ES
dc.subjectlesión renal agudaes-ES
dc.subjectperfusiónes-ES
dc.titleVeterinary perspective of the renal system in sepsisen-US
dc.titlePerspectiva veterinaria del sistema renal en la sepsises-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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