Peritoneal leiomyosarcoma in a canine: case report

Leiomiosarcoma peritoneal en un canino: reporte de caso

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dc.date2019-10-07
dc.date.accessioned2022-12-15T14:43:02Z
dc.date.available2022-12-15T14:43:02Z
dc.identifierhttps://revistamvz.unicordoba.edu.co/article/view/1363
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5353292
dc.descriptionThe purpose of this study is to present a peritoneal leiomyosarcoma in a canine and its histopathological and immunohistochemical findings. The patient, a 5-year old female Chow-Chow, was brought to Los Llanos University veterinary clinic due to loss of appetite, prostration and poor corporal condition. Physical examination showed pale mucous membranes, increased abdominal silhouette with a serosanguineous fluid content. Palpation at the cranial epigastrium evidenced a painless mass of hard consistency, irregular surface and caudally displaceable. Serum biochemical abnormalities included increased plasma total protein, globulin and creatinine. Thus, an exploratory laparotomy was performed, identifying a mass in the mesentery attached to a portion of the small intestine. In its report it was stated the following macroscopic findings: a firm mass of 18 cm long and 13 cm wide, with irregular surface, great vascularization. Tissue samples were fixed in 10% buffered formalin for histopathological and immunohistochemical analysis. Samples were processed by routine methods for microscopy and stained with hematoxylin-eosin (HE), Masson trichrome, anti-cytokeratin CK5, anti-smooth muscle actin, vimentin and KIT(CD117) antibodies. In conclusion, the tumor was classified by histopathology as of mesenchymal origin and internal diffuse cytoplasmic immunopositivity of neoplastic cells for smooth muscle actin, vimentin and was negative for KIT led to diagnose of leiomyosarcoma.en-US
dc.descriptionEl propósito de este estudio fue para presentar y documentar un leiomiosarcoma peritoneal en un canino y sus hallazgos histopatológicos e Inmunohistoquímica. El paciente, una hembra de 5 años de edad, de raza Chow-Chow, fue llevada a la Clínica Veterinaria de la Universidad de los Llanos, debido a pérdida de peso, postración y baja condición corporal. Al examen físico presentó mucosas pálidas, aumento de la silueta abdominal con contenido de fluido serosanguinolento. A la palpación se evidenció en el epigastrio craneal una masa no dolorosa, de consistencia dura, de superficie irregular y desplazable caudalmente. Anormalidades bioquímicas séricas incluyeron proteínas totales plasmáticas aumentadas, globulina y creatinina. Así, una laparotomía exploratoria fue realizada, identificando una masa en el mesenterio unida a la porción de intestino grueso. En el reporte se señalaron los siguientes hallazgos macroscópicos: una masa firme de 18 cm de longitud y 13 cm de ancho, con una superficie irregular, gran vascularización. Las muestras de tejido fueron fijadas en formalina buferada al 10% para análisis histopatológico e Inmunohistoquímica. Las muestras fueron procesadas por los métodos de rutina para microscopía y coloración con hematoxilina-eosina (HE), tricrómico de Masson, anticuerpos anti-citoqueratina CK5, anti-actina de músculo liso, vimentina y KIT(CD117). En conclusión, el tumor fue clasificado por histopatología como de origen mesenquimal e inmunopositividad citoplasmática difusa interna de células neoplásicas para actina de músculo liso, vimentina y negatividad para KIT, condujo al diagnóstico de leiomiosarcoma.es-ES
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dc.languagespa
dc.languageeng
dc.publisherUniversidad de Córdobaes-ES
dc.relationhttps://revistamvz.unicordoba.edu.co/article/view/1363/2240
dc.relationhttps://revistamvz.unicordoba.edu.co/article/view/1363/2241
dc.relationhttps://revistamvz.unicordoba.edu.co/article/view/1363/2260
dc.relationhttps://revistamvz.unicordoba.edu.co/article/view/1363/2262
dc.relationhttps://revistamvz.unicordoba.edu.co/article/view/1363/2264
dc.relationhttps://revistamvz.unicordoba.edu.co/article/view/1363/2265
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dc.sourceJournal MVZ Cordoba; Vol. 24 No. 3 (2019): Journal MVZ Córdoba Volumen 24(3) Septiembre-Diciembre 2019; 7378-7383en-US
dc.sourceRevista MVZ Córdoba; Vol. 24 Núm. 3 (2019): Revista MVZ Córdoba Volumen 24(3) Septiembre-Diciembre 2019; 7378-7383es-ES
dc.source1909-0544
dc.source0122-0268
dc.source10.21897/rmvz.v24i.n3.2019
dc.subjectGastrointestinalen-US
dc.subjectperroen-US
dc.subjectsistema digestivoen-US
dc.subjectneoplasiasen-US
dc.subjecttumoresen-US
dc.subjectDigestive systemes-ES
dc.subjectdoges-ES
dc.subjectgastrointestinales-ES
dc.subjectneoplasmses-ES
dc.subjecttumorses-ES
dc.titlePeritoneal leiomyosarcoma in a canine: case reporten-US
dc.titleLeiomiosarcoma peritoneal en un canino: reporte de casoes-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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