dc.creatorMontes Grajales, Diana Lucía
dc.creatorOlivero Vebel, Jesús
dc.date2019-04-01T00:03:14Z
dc.date2019-04-01T00:03:14Z
dc.date2014
dc.date.accessioned2022-12-07T14:47:36Z
dc.date.available2022-12-07T14:47:36Z
dc.identifier0300-483X
dc.identifierhttp://repositorio.colciencias.gov.co/handle/11146/34170
dc.identifierContiene 42 referencias bibliográficas. Véase documento adjunto
dc.identifier10.1016/j.tox.2014.11.006
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/5301351
dc.descriptionEndocrine disrupting chemicals (EDCs) are a group of compounds that affect the endocrine system, frequently found in everyday products and epidemiologically associated with several diseases. The purpose of this work was to develop EDCs DataBank, the only database of EDCs with three-dimensional structures. This database was built on MySQL using the EU list of potential endocrine disruptors and TEDX list. It contains the three-dimensional structures available on PubChem, as well as a wide variety of information from different databases and text mining tools, useful for almost any kind of research regarding EDCs. The web platform was developed employing HTML, CSS and PHP languages, with dynamic contents in a graphic environment, facilitating information analysis. Currently EDCs DataBank has 615 molecules, including pesticides, natural and industrial products, cosmetics, drugs and food additives, among other low molecular weight xenobiotics. Therefore, this database can be used to study the toxicological effects of these molecules, or to develop pharmaceuticals targeting hormone receptors, through docking studies, high-throughput virtual screening and ligand-protein interaction analysis
dc.descriptionDepartamento Administrativo de Ciencia, Tecnología e Innovación [CO] Colciencias
dc.description5507-543-31904
dc.descriptionPrograma: Bioprospección y desarrollo de ingredientes naturales para las industrias cosmética, farmacéutica y de productos de aseo con base en la biodiversidad colombiana
dc.descriptionno
dc.formatpdf
dc.format8 páginas
dc.formatapplication/pdf
dc.languageeng
dc.relationPrograma: Bioprospección y desarrollo de ingredientes naturales para las industrias cosmética, farmacéutica y de productos de aseo con base en la biodiversidad colombiana. La publicación completa está disponible en : <a href="http://repositorio.colciencias.gov.co/handle/11146/34163" target="blank">http://repositorio.colciencias.gov.co/handle/11146/34163</a>
dc.rightsinfo:eu-repo/semantics/openAccess
dc.sourceToxicology 327 (2015) 87-94
dc.subjectSistema endocrino
dc.subjectBiomasa
dc.subjectXenobiotic
dc.subjectEndocrine disruptor
dc.subjectDatabase
dc.subjectVirtual screening
dc.subjectComputational toxicology
dc.subjectAceites esenciales
dc.subjectBiología molecular
dc.subjectAceites vegetales
dc.subjectTecnología química
dc.subjectQuímica agrícola
dc.titleEDCs DataBank: 3D-Structure database of endocrine disrupting chemicals
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.coverageColombia


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