dc.creator | Ayu Rezkitha, Yudith Annisa | |
dc.creator | Aji Savitri, Camilia Metadea | |
dc.creator | Lusida, Maria Inge | |
dc.creator | Yudho Bintoro, Siprianus Ugroseno | |
dc.creator | Rahmawati, Lita Diah | |
dc.creator | I’tishom, Reny | |
dc.creator | Miftahussurur, Muhammad | |
dc.date | 2022-07-11 | |
dc.date.accessioned | 2022-10-28T12:07:45Z | |
dc.date.available | 2022-10-28T12:07:45Z | |
dc.identifier | http://saber.ucv.ve/ojs/index.php/rev_gmc/article/view/24057 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/4955933 | |
dc.description | Colorectal cancer (CRC) is the fourth leading cause of cancer-related deaths worldwide. Various genetic and epigenetic changes in colonic epithelial cells, including DNA methylation, histone modifications, and noncoding RNAs, were involved in the initiation and progression of CRC. Moreover, epigenetic changes played an important role in CRC drug resistance. The dynamic and reversibility of epigenetic changes provide new possible therapeutic targets for colorectal cancer. | es-ES |
dc.format | application/pdf | |
dc.language | spa | |
dc.publisher | Academia Nacional de Medicina venezolana. | es-ES |
dc.relation | http://saber.ucv.ve/ojs/index.php/rev_gmc/article/view/24057/144814490431 | |
dc.rights | Derechos de autor 2022 Gaceta Médica de Caracas | es-ES |
dc.rights | http://creativecommons.org/licenses/by-nc/4.0 | es-ES |
dc.source | Gaceta Médica de Caracas; Vol. 130 Núm. 2 (2022) | es-ES |
dc.source | 2739-0012 | |
dc.source | 0367-4762 | |
dc.subject | Colorectal cancer | es-ES |
dc.subject | epigenetics | es-ES |
dc.subject | DNA methylation | es-ES |
dc.subject | histone modification | es-ES |
dc.subject | RNA therapeutics | es-ES |
dc.subject | cancer | es-ES |
dc.title | Epigenetic Approach on Colorectal Cancer Systemic Therapy: Promising yet a Long Way to Go | es-ES |
dc.type | info:eu-repo/semantics/article | |
dc.type | info:eu-repo/semantics/publishedVersion | |
dc.coverage | Indonesia | es-ES |