| dc.creator | Hernández, Harold | |
| dc.creator | Fernandes, Andreina | |
| dc.creator | Escalona, Laura | |
| dc.creator | Correnti, María | |
| dc.date | 2017-10-30T18:18:59Z | |
| dc.date | 2017-10-30T18:18:59Z | |
| dc.date | 2016-03-26 | |
| dc.date.accessioned | 2022-10-28T01:28:01Z | |
| dc.date.available | 2022-10-28T01:28:01Z | |
| dc.identifier | 2333-9721 | |
| dc.identifier | http://hdl.handle.net/10872/16942 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/4950470 | |
| dc.description | Recent investigations suggest that the viruses of the family Herpesviridae are associated with pe- riodontal disease, demonstrating a possible association with the presence of Human Cytomegalo- virus (HCMV), Herpes Simplex Virus 1 (HSV-1) and Epstein Barr Virus (EBV) in periodontal tissues. Aim: To analyze the association between the presence of HSV-1, HCMV and EBV in patients with chronic or aggressive periodontitis. Methods: Crevicular fluid samples were collected from 11 pa- tients with aggressive periodontitis (AgP), 11 with chronic periodontitis (CP) and 11 healthy con- trol subjects (CG). The following clinical parameters were measured: plaque index (PI), bleeding on probing (BOP), probing depths (PD) and clinical attachment loss (CAL). Viral detection was performed by PCR for HSV-1, HCMV and EBV. Results: HCMV was detected in 27.3% of AgP patients but not detected in CP and healthy subjects; HSV-1 in 27.3% of AgP and CP group and in 9.1% of CG. EBV-1 was detected in 18.2% of CP patients and 9.1% of the CG. HCMV and HSV-1 coinfection was detected in 18.8% of AgP patients and 9.09% of viral coinfection between HSV-1 and VEB, within the CP group. The AgP group exhibited the higher values for all clinical parameters evaluated, re- spect to the CP and control group. Conclusion: The presence of HCMV may be related to periodon- tal disease, specifically in cases of AgP, and it may play a synergistic role with other infectious agents from the oral cavity associated with the development of periodontitis. | |
| dc.description | FONACIT, projecto No. G-2005000408. | |
| dc.language | en | |
| dc.publisher | Open Access Library Journal | |
| dc.subject | Periodontitis | |
| dc.subject | Gingival Crevicular FLuid | |
| dc.subject | Cytomegalovirus | |
| dc.subject | Herpes Simplex Virus | |
| dc.subject | Barr Virus | |
| dc.title | Herpes Simplex Virus 1, Cytomegalovirus and Epstein Barr Virus Detection in Patients with Chronic and Aggressive Periodontitis | |
| dc.type | Article | |
