Aporphine Alkaloids from Guatteria stenopelata (Annonaceae)

dc.creatorRodríguez, María del C.
dc.creatorBastidas, Elsy
dc.creatorRodríguez, Mildred
dc.creatorLucena, Edgard
dc.creatorCastillo, Anibal
dc.creatorHasegawa, Masahisa
dc.date2017-01-19T15:45:05Z
dc.date2017-01-19T15:45:05Z
dc.date2008
dc.date.accessioned2022-10-28T01:20:09Z
dc.date.available2022-10-28T01:20:09Z
dc.identifierVolumen 3, Number 4, Pages 515-518 (2008)
dc.identifier1555-9475
dc.identifierhttp://hdl.handle.net/10872/14052
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4947693
dc.descriptionGuatteria species (Annonaceae) are rich in isoquinoline alkaloids that contain a restricted beta phenethylamine moiety and thus have potential monoamine oxidase (MAO) inhibitor for treatment of Alzheimer´s and Parkinson´s diseases. Three aporphine alkaloids have bee isolate from G. stenopelata, the know oxoaporphine dicentrinone (1), and two novel compounds, N-methyldicentrinone (2) and 4,5-dioxodehydrodixentrine (3). Their inhibitory effects on MAO-B were evaluated, but none of them was significantly active.
dc.languageen
dc.publisherNatural Products Communications
dc.subjectGuatteria stenopelata
dc.subjectdicentrinone
dc.subjectN-methyldicentrinone
dc.subject4,5-dioxodehydrodixentrine
dc.subjectMAO-B
dc.subjectAnnonaceae
dc.subjectporphine alkaloids
dc.titleAporphine Alkaloids from Guatteria stenopelata (Annonaceae)
dc.typeArticle


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