FURTHER ASPECTS OF T CELL FUNCTION IN SYSTEMIC LUPUS ERYTHEMATOSUS

dc.creatorDefreitas, M. E.
dc.creatorKondracki, E.
dc.creatorPérez -Rojas, G.
dc.creatorBianco Colmenares, Nicolás E.
dc.date2016-12-13T16:34:45Z
dc.date2016-12-13T16:34:45Z
dc.date1982
dc.date.accessioned2022-10-28T01:19:51Z
dc.date.available2022-10-28T01:19:51Z
dc.identifier0090-0877
dc.identifierhttp://hdl.handle.net/10872/13944
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4947587
dc.descriptionGeneration of effector cells, the expression of cell mediated lympholysis (CML) and the reactivity of mononuclear cells in solid cultures, were explored in patients with Systemic Lupus Erythematosus (SLE). While proliferative responses to alloantigens were comparable to the controls, a significant decrease in CML capacity was found in SLE T lymphocytes; Further, T cells stimulated with T cell mitogen in solid cultures showed diminished proliferative response to soluble factors. Functional cell interaction defects rather than intrinsic T cell abnormalities may be operating in SLE.
dc.languageen
dc.publisherIMMNOLOGICAL COMMUNICATIONS
dc.relationVol.11;Nº 2 pag 113-120
dc.subjecteffector cells
dc.subjectlympholysis
dc.subject(CML)
dc.subjectmononuclear cells
dc.subjectT cell mitogen
dc.subjectSystemic Lupus Erythematosus
dc.subject(SLE)
dc.subjectT lymphocytes
dc.titleFURTHER ASPECTS OF T CELL FUNCTION IN SYSTEMIC LUPUS ERYTHEMATOSUS
dc.typeArticle


Este ítem pertenece a la siguiente institución