| dc.creator | Zénzola, Victor | |
| dc.creator | Bolivar, Efren | |
| dc.creator | Betancourt, Luis | |
| dc.creator | Salas Rodriguez, Joanne | |
| dc.creator | Jiménez, Reina | |
| dc.creator | Guerra, Marcos | |
| dc.creator | Carrero, Nelly | |
| dc.creator | Bérgamo, Laura | |
| dc.creator | Godoy, Ali Josue | |
| dc.creator | Romero, Gabriel | |
| dc.creator | Pasquale, Giuseppe | |
| dc.creator | Martinez, Pedro | |
| dc.creator | Ruiz, Angela | |
| dc.date | 2014-05-31T22:05:51Z | |
| dc.date | 2014-05-31T22:05:51Z | |
| dc.date | 2011-09 | |
| dc.date.accessioned | 2022-10-28T00:59:10Z | |
| dc.date.available | 2022-10-28T00:59:10Z | |
| dc.identifier | ZENZOLA, Víctor et al. Factores clínico-patológicos en cáncer de mama relación con metástasis en ganglios no centinelas axilares cuando el centinela es positivo. Rev. venez. oncol. [online]. 2011, vol.23, n.3, pp. 134-144 | |
| dc.identifier | 0798-0582 | |
| dc.identifier | http://hdl.handle.net/10872/6482 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/4940613 | |
| dc.description | OBJECTIVE: Our aim was to determine which clinic
pathologic factors can predict involve of non sentinel lymph
nodes when the sentinel lymph node biopsy is positive, so
to omit the axillaries lymph node dissection. METHODS:
The data of all patients with invasive breast carcinoma,
between 2000 and April 2010, who underwent (271),
was reviewed. We excluded the patients who received
neo adjuvant therapy, remaining 219 patients. Univariate
(Chi square test), and multivariate analysis in a logistical
regression model was used to establish the association
within some clinic pathologic factors and involve of
non sentinel nodes in the group of patients with positive
RESULTS: Positive sentinel was found in 44 patients
(20.%). Non sentinel positive lymph nodes were recorded
in 22 (50 %). Nuclear grade III, lymph vascular invasion
and number of positive sentinel nodes (2 or more) were
associated with residual axillaries disease in the univariate
analysis. In the multivariate analysis only lymph vascular
invasion was an independent predictor of metastases in non
sentinel lymph nodes. CONCLUSION: Lymph vascular
invasion enhances the chance of axillaries residual disease
in patients with positive biopsy. The residual disease after
positive biopsy is significant (50 %).We can´t find a group
of factors that could help to decide in which patients we
can omit the axillaries dissection. There is some evidence
that chemotherapy and radiotherapy can control axillaries
residual disease. Even in this context all patients with
positive sentinel biopsy must undergo axillaries dissection. | |
| dc.description | TRABAJO GANADOR PREMIO DR. ALEJANDRO CALVO LAIRET. | |
| dc.language | es | |
| dc.publisher | Rev Venez Oncol | |
| dc.subject | Cáncer, mama, ganglio, centinela, factores predictores, ganglios no centinelas. | |
| dc.subject | Breast, cancer, sentinel, lymph node, predictor factors, non sentinel. | |
| dc.title | FACTORES CLÍNICO-PATOLÓGICOS EN CÁNCER DE MAMA RELACIÓN CON METÁSTASIS EN GANGLIOS NO CENTINELAS AXILARES CUANDO EL CENTINELA ES POSITIVO | |
| dc.type | Article | |
