dc.creator | Tejada, Romina A. | |
dc.creator | Vargas, Kris G. | |
dc.creator | Benites-Zapata, Vicente | |
dc.creator | Mezones-Holguín, Edward | |
dc.creator | Bolaños-Díaz, Rafael | |
dc.creator | Hernández, Adrian V. | |
dc.date.accessioned | 2020-06-03T21:50:55Z | |
dc.date.accessioned | 2022-10-25T19:35:56Z | |
dc.date.available | 2020-06-03T21:50:55Z | |
dc.date.available | 2022-10-25T19:35:56Z | |
dc.date.created | 2020-06-03T21:50:55Z | |
dc.date.issued | 2017-01-03 | |
dc.identifier | Tejada R., Vargas K., Benites V., Mezones E., Bolaños R., Hernández A. Human papillomavirus vaccine efficacy in the prevention of anogenital warts: systematic review and meta-analysis. Salud Pública de México. 2017; 59(1): 84-94. | |
dc.identifier | 1606-7916 | |
dc.identifier | https://hdl.handle.net/20.500.12727/6137 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/4791949 | |
dc.description.abstract | Objective:: To review evidence on the efficacy of HPV vaccines in the prevention of non-cancer lesions (anogenital warts [AGW], recurrent laryngeal papillomatosis and oral papillomatosis).
Materials and methods:: We conducted a systematic review of randomized trials. We performed random effect models and effects were reported as relative risks (RR) and their confidence intervals (95%CI) following both intention to treat (ITT) and per protocol (PP) analyses.
Results:: We included six studies (n=27 078). One study was rated as high risk of bias. One study could not be included in the meta-analysis because it provided combined results. We found that quadrivalent vaccine reduced the risk of AGW by 62% (RR: 0.38, 95%CI:0.32-0.45, I2:0%) in the ITT analysis and by 95% (RR: 0.05, 95%CI:0.01-0.25, I2:66%) in the PP analysis. Subgroup analyses of studies in women or with low-risk of bias provided similar results.
Conclusion:: HPV quadrivalent vaccine is efficacious in preventing AGW in men and women. | |
dc.language | eng | |
dc.publisher | Instituto Nacional de Salud Pública | |
dc.relation | Salud Pública de México;vol. 59, no. 1 | |
dc.relation | https://www.scielosp.org/article/spm/2017.v59n1/84-94/en/ | |
dc.relation | http://dx.doi.org/10.21149/7824 | |
dc.rights | http://creativecommons.org/licenses/by-nc-sa/4.0/ | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.source | Repositorio Académico USMP | |
dc.source | Universidad San Martín de Porres - USMP | |
dc.subject | Enfermedades del ano | |
dc.subject | Vacunas contra papillomavirus | |
dc.subject | Condiloma acuminado | |
dc.subject | Ensayos clínicos controlados aleatorios como asunto | |
dc.subject | Enfermedades de los genitales femeninos | |
dc.subject | Enfermedades de los genitales masculinos | |
dc.title | Human papillomavirus vaccine efficacy in the prevention of anogenital warts: systematic review and meta-analysis | |
dc.type | Artículos de revistas | |