dc.date.accessioned2022-02-01T21:18:27Z
dc.date.available2022-02-01T21:18:27Z
dc.date.created2022-02-01T21:18:27Z
dc.date.issued2021
dc.identifierhttps://hdl.handle.net/20.500.12866/11296
dc.identifierhttps://doi.org/10.17843/rpmesp.2021.381.6727
dc.description.abstractThe present report is the original description of blaTEM-176. The mechanisms of resistance to antimicrobial agents were determined in an enterotoxigenic Escherichia coli, determining the susceptibility to 22 antimicrobials classified in 15 different groups by agar diffusion and establishing the phylogenetic group, mechanisms of resistance and presence of Class 1 and 2 integrons. Integrons and β-lactam resistance genes were sequenced. The isolate, belonging to phylogenetic group A, showed the presence of resistance or diminished susceptibility to a ampicillin, amoxicillin plus clavulanic acid, nalidíxic acid, ciprofloxacin, streptomycin, kanamycin, tetracycline, trimethoprim, sulfisoxazole, cotrimoxazole, azithromycin and nitrofurantoin, carrying blaTEM, aadA1/2, aphA1, sul3, tet(A) and a Class 2 integron containing a dfrA1 gene. Quinolone resistance was related to the substitution Ser83 Ala. The TEM sequencing showed the presence of the new substitution Ala222 Val, which led to the description of the new β-lactamase blaTEM-176
dc.languagespa
dc.publisherInstituto Nacional de Salud
dc.relationRevista Peruana de Medicina Experimental y Salud Publica
dc.relation1726-4642
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectalanine
dc.subjectArticle
dc.subjectgenetics
dc.subjectnonhuman
dc.subjectantibiotic resistance
dc.subjectantibiotic sensitivity
dc.subjectEscherichia coli
dc.subjectmultidrug resistance
dc.subjectcotrimoxazole
dc.subjectampicillin
dc.subjectbacterial gene
dc.subjectgene sequence
dc.subjectphylogeny
dc.subjectazithromycin
dc.subjectAnti-Bacterial Agents
dc.subjectantiinfective agent
dc.subjectbeta lactamase
dc.subjectbeta-Lactamases
dc.subjectintegron
dc.subjectIntegrons
dc.subjectmetabolism
dc.subjectMicrobial Sensitivity Tests
dc.subjectDrug Resistance, Bacterial
dc.subjectPhylogeny
dc.subjectkanamycin
dc.subjectstreptomycin
dc.subjectamoxicillin plus clavulanic acid
dc.subjectciprofloxacin
dc.subjectnalidixic acid
dc.subjectnitrofurantoin
dc.subjecttetracycline
dc.subjecttrimethoprim
dc.subjectmicrobial sensitivity test
dc.subjectDrug Resistance, Multiple, Bacterial
dc.subjectmolecular epidemiology
dc.subjectaadA1 gene
dc.subjectaadA2 gene
dc.subjectamino acid substitution
dc.subjectAmoxicillin-Clavulanic Acid
dc.subjectAmpicillin
dc.subjectAntibacterial Drug Resistance
dc.subjectaphA1 gene
dc.subjectBeta-Lactamases
dc.subjectblaTEM gene
dc.subjectdfrA1 gene
dc.subjectEnterotoxigenic Escherichia coli
dc.subjectIntegrons (source: MeSH NLM)
dc.subjectMolecular Epidemiology
dc.subjectquinolone
dc.subjectsul3 gene
dc.subjectsulfafurazole
dc.subjectvaline
dc.titleCaracterización de Escherichia coli D7111 productora de β-lactamasa TEM-176
dc.typeinfo:eu-repo/semantics/article


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