dc.date.accessioned2022-01-18T19:26:53Z
dc.date.available2022-01-18T19:26:53Z
dc.date.created2022-01-18T19:26:53Z
dc.date.issued2011
dc.identifierhttps://hdl.handle.net/20.500.12866/10984
dc.identifierhttps://doi.org/10.1111/j.1469-0691.2011.03640.x
dc.description.abstractThis review gives an update of current knowledge on the clinical pleiomorphism of Leishmania, with a special emphasis on the case of asymptomatic carriage. The first part describes the numerous unusual expressions of the disease that occur besides the classic (visceral, cutaneous, and mucocutaneous) forms of leishmaniases. The second part deals with progress in the understanding of disease outcome in humans, and the possible future approaches to improve our knowledge in the field. The third part highlights the role of the too often neglected asymptomatic carrier compartment. This group could be key to understanding infraspecific differences in virulence and pathogenicity of the parasite, as well as identifying the genetic determinants involved in the expression of the disease.
dc.languageeng
dc.publisherElsevier
dc.relationClinical Microbiology and Infection
dc.relation1469-0691
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectPathogenicity
dc.subjectAsymptomatic Infection
dc.subjectDisease Transmission
dc.subjectParasite Virulence
dc.subjectReview
dc.subjectDisease Course
dc.subjectSkin Leishmaniasis
dc.subjectGenetic Polymorphism
dc.subjectLeishmaniasis
dc.subjectPathogenesis
dc.subjectSpecies Difference
dc.subjectImmune Response
dc.subjectAsymptomatic Carriage
dc.subjectClinical Diversity
dc.subjectHost Susceptibility
dc.subjectParasite Genetic Diversity
dc.subjectPleiotropy
dc.subjectUnusual Clinical Forms
dc.subjectVisceral Leishmaniasis
dc.titleClinical pleiomorphism in human leishmaniases, with special mention of asymptomatic infection
dc.typeinfo:eu-repo/semantics/review


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