dc.date.accessioned2022-01-18T19:26:52Z
dc.date.available2022-01-18T19:26:52Z
dc.date.created2022-01-18T19:26:52Z
dc.date.issued2012
dc.identifierhttps://hdl.handle.net/20.500.12866/10979
dc.identifierhttps://doi.org/10.1111/j.1439-0272.2011.01165.x
dc.description.abstractMashua is an edible-tuber crop that grows in the Andean region. Folk medicine describes the use of mashua to reduce reproductive function in men. The present study aimed: (i) to determine whether different doses of mashua (0.01, 0.1, 1 and 2 g kg(-1)) produced a dose-response reduction on sperm production and quality; and, (ii) to determine whether these anti-reproductive effects of mashua can be reversible after cessation of treatment (12 and 24 days of recovery time). Mashua-treated rats showed lower values of daily sperm production, epididymal and vas deferens sperm count and sperm motility; meanwhile, mashua increased the percentage of abnormal sperm morphology and epididymal sperm transit rate. The following variables follow a dose-response effect: sperm number in vas deferens, sperm motility and sperm transit rate. In addition, it was demonstrated that the reduction in reproduction function in male rats treated with mashua was reversible after 24 days of recovery time. Finally, lower doses mashua reduces sperm number and quality (motility and morphology), and these adverse effects on male reproductive system may be reversible after 24 days after cessation of the treatment.
dc.languageeng
dc.publisherWiley
dc.relationAndrologia
dc.relation1439-0272
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectanimal experiment
dc.subjectAnimals
dc.subjectnon|morphology
dc.subjectunclassified drug
dc.subjectdose response
dc.subjectreproduction
dc.subjectDaily sperm production
dc.subjectDose-Response Relationship, Drug
dc.subjectEpididymal sperm transit
dc.subjectepididymis
dc.subjectmale genital system
dc.subjectMashua
dc.subjectplant extract
dc.subjectPlant Extracts
dc.subjectrat
dc.subjectRats
dc.subjectRats, Sprague-Dawley
dc.subjectSperm Count
dc.subjectSperm Motility
dc.subjectSperm motility and morphology
dc.subjectSperm number
dc.subjectspermatogenesis
dc.subjectSpermatozoa
dc.subjectspermatozoon count
dc.subjectspermatozoon motility
dc.subjectTropaeolaceae
dc.subjectTropaeolum
dc.subjectTropaeolum tuberosum extract
dc.subjectvas deferens
dc.titleEvaluation of different doses of mashua (Tropaeolum tuberosum) on the reduction of sperm production, motility and morphology in adult male rats.
dc.typeinfo:eu-repo/semantics/article


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