dc.date.accessioned | 2022-01-04T20:30:00Z | |
dc.date.accessioned | 2022-10-25T18:47:49Z | |
dc.date.available | 2022-01-04T20:30:00Z | |
dc.date.available | 2022-10-25T18:47:49Z | |
dc.date.created | 2022-01-04T20:30:00Z | |
dc.date.issued | 2014 | |
dc.identifier | https://hdl.handle.net/20.500.12866/10519 | |
dc.identifier | International Journal of Infectious Diseases | |
dc.identifier | https://doi.org/10.1016/j.ijid.2013.10.005 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/4785010 | |
dc.description.abstract | To evaluate the presence of human T-lymphotropic virus type 1 (HTLV-1) infection in isolated rural communities in the southern Andes of Peru. We conducted a cross-sectional study in five communities located in three provinces in Ayacucho, Peru. The five communities are located at >3000 meters above sea level and are mainly rural, and more than 85% of the population speaks Quechua. Volunteers aged 12 years and older were included. Clinical and epidemiological data were collected, along with a blood sample for serological testing. We included 397 participants; their median age was 41 years (interquartile range 31–57 years) and 69% were women. According to our definitions, 98% were of Quechua origin. HTLV-1 was diagnosed in 11 people: 0/164 in Cangallo, 3/154 (2%) in Vilcashuaman, and 8/79 (10%) in Parinacochas. There were no cases of HTLV-2. All the HTLV-1-positive participants were born in Ayacucho and were of Quechua origin; they ranged in age from 29 to 87 years (median 56 years) and 10/11 were women. Ten were apparently healthy, and one woman was diagnosed with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Three out of 11 had a family member with a lower limb impairment compatible with HAM/TSP. The fact that HTLV-1 infection was present in two out of three provinces suggests that HTLV-1 could be highly endemic in the southern Andes in the Quechua population. | |
dc.language | eng | |
dc.publisher | Elsevier | |
dc.relation | urn:issn:1878-3511 | |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.subject | Prevalence | |
dc.subject | Human T-lymphotropic virus type 1 | |
dc.subject | Andes | |
dc.subject | Peru | |
dc.subject | Breastfeeding | |
dc.title | Human T-lymphotropic virus type 1 infection is frequent in rural communities of the southern Andes of Peru | |
dc.type | Artículos de revistas | |