Myocardial Inflammation and Edema in People Living With Human Immunodeficiency Virus

Abstract

The burden of cardiovascular disease in people living with HIV (PLWH) has tripled over the last 20 years, with cardiac manifestations of disease ranging from coronary disease to heart failure (1). The pathophysiological mechanisms involved in the development of HIV cardiomyopathy remain elusive. Subclinical structural and functional changes have been demonstrated in PLWH, but studies that used advanced imaging techniques focused on patients already treated with antiretroviral therapy (ART), potentially limiting the understanding of cardiac manifestations of HIV...