dc.date.accessioned2019-07-04T16:59:36Z
dc.date.available2019-07-04T16:59:36Z
dc.date.created2019-07-04T16:59:36Z
dc.date.issued2019
dc.identifierhttps://hdl.handle.net/20.500.12866/6804
dc.identifierhttps://doi.org/10.1186/s13071-019-3498-4
dc.description.abstractBACKGROUND: In the Amazon Basin, Nyssorhynchus (Anopheles) darlingi is the most aggressive and effective malaria vector. In endemic areas, behavioral aspects of anopheline vectors such as host preference, biting time and resting location post blood meal have a key impact on malaria transmission dynamics and vector control interventions. Nyssorhynchus darlingi presents a range of feeding and resting behaviors throughout its broad distribution. METHODS: To investigate the genetic diversity related to biting behavior, we collected host-seeking Ny. darlingi in two settlement types in Acre, Brazil: Granada (~ 20-year-old, more established, better access by road, few malaria cases) and Remansinho (~ 8-year-old, active logging, poor road access, high numbers malaria cases). Mosquitoes were classified by the location of collection (indoors or outdoors) and time (dusk or dawn). RESULTS: Genome-wide SNPs, used to assess the degree of genetic divergence and population structure, identified non-random distributions of individuals in the PCA for both location and time analyses. Although genetic diversity related to behavior was confirmed by non-model-based analyses and FST values, model-based STRUCTURE detected considerable admixture of these populations. CONCLUSIONS: To our knowledge, this is the first study to detect genetic markers associated with biting behavior in Ny. darlingi. Additional ecological and genomic studies may help to understand the genetic basis of mosquito behavior and address appropriate surveillance and vector control.
dc.languageeng
dc.publisherBioMed Central
dc.relationParasites and Vectors
dc.relation1756-3305
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectanimal
dc.subjectAnimals
dc.subjectAnopheles
dc.subjectArticle
dc.subjectbites and stings
dc.subjectBites and Stings
dc.subjectBiting behavior
dc.subjectBrazil
dc.subjectecology
dc.subjectEcology
dc.subjectfeeding behavior
dc.subjectFeeding Behavior
dc.subjectfemale
dc.subjectFemale
dc.subjectGenetic heterogeneity
dc.subjectgenetic marker
dc.subjectGenetic population
dc.subjectgenetic variability
dc.subjectgenetic variation
dc.subjectGenetic Variation
dc.subjectgenetics
dc.subjectGenome, Insect
dc.subjectgenotype
dc.subjectGenotype
dc.subjectgeography
dc.subjectGeography
dc.subjectIndividual mosquito scale
dc.subjectinsect bite
dc.subjectinsect genome
dc.subjectMalaria vector
dc.subjectmale
dc.subjectMale
dc.subjectmosquito
dc.subjectmosquito control
dc.subjectMosquito Control
dc.subjectNyssorhynchus (Anopheles) darlingi
dc.subjectNyssorhynchus darlingi
dc.subjectPolymorphism, Single Nucleotide
dc.subjectpopulation structure
dc.subjectprincipal component analysis
dc.subjectsingle nucleotide polymorphism
dc.subjectSNPs
dc.subjecttime
dc.titleGenetic diversity of Nyssorhynchus (Anopheles) darlingi related to biting behavior in western Amazon
dc.typeinfo:eu-repo/semantics/article


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