Treponema pallidum pallidum Genotypes and Macrolide Resistance Status in Syphilitic Lesions among Patients at 2 Sexually Transmitted Infection Clinics in Lima, Peru

dc.date.accessioned2019-02-06T14:51:19Z
dc.date.available2019-02-06T14:51:19Z
dc.date.created2019-02-06T14:51:19Z
dc.date.issued2016
dc.identifierhttps://hdl.handle.net/20.500.12866/5209
dc.identifierhttps://doi.org/10.1097/OLQ.0000000000000465
dc.description.abstractWe report the circulating genotypes and the frequency of macrolide-resistance patterns among Treponema pallidum pallidum DNA isolated from syphilitic lesions from patients who attended 2 sexual health clinics in Lima, Peru. We implemented and used a molecular typing scheme to describe local T. pallidum pallidum strains. Among 14 specimens, subtype 14d/f was the most prevalent strain in 7 fully typed T. pallidum DNA specimens obtained from men who have sex with men and transgender women presenting with chancre-like lesions. No macrolide-resistance mutations were found in T. pallidum DNA from 10 lesions.
dc.languageeng
dc.publisherWolters Kluwer Health
dc.relationSexually Transmitted Diseases
dc.relation1537-4521
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectDrug Resistance, Bacterial
dc.subjectFemale
dc.subjectGenotype
dc.subjectHomosexuality, Male
dc.subjectHumans
dc.subjectMacrolides/pharmacology
dc.subjectMale
dc.subjectMolecular Typing
dc.subjectMutation
dc.subjectPeru/epidemiology
dc.subjectSexually Transmitted Diseases, Bacterial/drug therapy/epidemiology/microbiology
dc.subjectSyphilis/drug therapy/epidemiology/microbiology
dc.subjectTransgender Persons
dc.subjectTreponema pallidum/classification/drug effects/genetics
dc.titleTreponema pallidum pallidum Genotypes and Macrolide Resistance Status in Syphilitic Lesions among Patients at 2 Sexually Transmitted Infection Clinics in Lima, Peru
dc.typeinfo:eu-repo/semantics/article


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