| dc.description.abstract | Background: The correct detection and intervention of diabetic nephropathy (ND) by identifying factors that
affect its progression is crucial to reduce its morbidity and mortality.
Objective: To determine the risk factors for deterioration of kidney function in patients with stage IV and V
diabetic nephropathy, at the José Carrasco Arteaga Hospital, Cuenca 2018-2019.
Methodology: An analytical study of cases and controls was carried out, with the medical records of 462
patients seen from 2018 to 2019 in the outpatient Nephrology and Endocrinology consultation of the José
Carrasco Arteaga Hospital, with the approval of the Bioethics Committee. The data were collected in a form
designed for this purpose and analyzed with SPSS version 15.0. Simple, double-entry tables and the statistician
(OR) were used to measure the relationship between the presence of diabetic nephropathy and risk factors.
Results: The mean age was 66.95 years, predominating men and older adults, mixed ethnicity (98.3%), basic
level of education (51.5%) and married (67.7%). Risk factors such as secondary hyperparathyroidism, arterial
hypertension (HTA), hyperphosphatemia, hyperuricemia, smoking, obesity, poor metabolic control, and
hypocalcemia are risk factors for DN in the study patients, while dyslipidemia, the absence of statin and ARM
use are not presented as risk factors for ND.
Conclusions: Biochemical indicators are more altered in patients with DN; bad habits (smoking); chronic
pathologies (hypertension, obesity) and poor metabolic control lead to deterioration of kidney function. | |
