dc.contributorFlores Fiallos, Linda Mariuxi
dc.contributorVillegas Freire, Cristina Nataly
dc.creatorLópez Manobanda, Cristian Jonny
dc.creatorMasabanda Carrillo, Héctor Fernando
dc.date.accessioned2022-09-20T17:30:32Z
dc.date.accessioned2022-10-20T18:59:30Z
dc.date.available2022-09-20T17:30:32Z
dc.date.available2022-10-20T18:59:30Z
dc.date.created2022-09-20T17:30:32Z
dc.date.issued2021-08-20
dc.identifierLópez Manobanda, Cristian Jonny; Masabanda Carrillo, Héctor Fernando. (2021). Evaluación de la actividad antioxidante: efectos hipoglucémicos a partir de la yaca (Artocarpus heterophyllus Lam). Escuela Superior Politécnica de Chimborazo. Riobamba.
dc.identifierhttp://dspace.espoch.edu.ec/handle/123456789/16996
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4583163
dc.description.abstractThe objective of this study was to evaluate the hypoglycaemic effect from hydroalcoholic and aqueous extracts of the leaves of the Jackfruit (Artocarpus heterophyllus Lam), basing their analysis on rats (Rattus norvegicus). Hydroalcoholic (70% isopropyl alcohol) and aqueous extracts were prepared at concentrations of 125, 250 and 400 ppm, respectively. In 30 days, the hypoglycaemic analysis was made, 45 male rats were used, which were divided into 9 groups of 5 rats each, blank, negative control, positive control, 3 groups for the hydroalcoholic extract of 125, 250 and 400 ppm and 3 groups for the aqueous extract at the same concentrations. The 8 groups, except the blank, were administered a diet rich in starch at a concentration of 2000 ppm (mg / Kg) of body weight for 15 days, thus affecting hyperglycaemia. After the starch diet, blood glucose was measured on 15 days, on the first, seventh and fifteenth day, at 30-, 60- and 120-minute intervals. The pharmacological effect was evidenced in both hydroalcoholic and aqueous extracts at a concentration of 400 ppm with a p-value less than 0.05 through statistical tests when comparing your results with the drug used commercially. In conclusion, the antioxidant activity, hypoglycaemic effects from the hydroalcoholic and aqueous extracts of the leaves of the Jackfruit (Artocarpus heterophyllus Lam) were evaluated. Identification and chemical purification studies of the active ingredient are recommended.
dc.languagespa
dc.publisherEscuela Superior Politécnica de Chimborazo
dc.relationUDCTFC;156T0030
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/3.0/ec/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTECNOLOGÍA Y CIENCIAS DE LA INGENIERÍA
dc.subjectQUÍMICA
dc.subjectTAMIZAJE FITOQUÍMICO
dc.subjectGLUCEMIA
dc.subjectYACA (Artocarpus heterophyllus Lam)
dc.subjectEXTRACTO HIDROALCOHÓLICO
dc.subjectEXTRACTO ACUOSO
dc.subjectRATAS (Rattus norvegicus)
dc.titleEvaluación de la actividad antioxidante: efectos hipoglucémicos a partir de la yaca (Artocarpus heterophyllus Lam)
dc.typeTesis


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