Determinación del marcador tumoral CA 125 por el método Elisa y su relación con los factores de riesgo en empleadas y docentes de la ESPOCH- 2019.

Abstract

The main objective of this research project was to determine the CA 125 tumor marker through the ELISA method and its connection with risk factors at ESPOCH employees and teachers, a survey was conducted in a target population of 99 to understand the biological risk factors, reproductive health history and lifestyles and blood extraction was performed by vein puncture, choosing 86 people based on these factors. These samples were processed in the Clinical Analysis laboratory at the ESPOCH faculty of Sciences; for CA 125 quantification, the enzyme-linked immunosorbent assay (ELISA) of the sandwich type was used. The statistical analysis was carried out by means of the evaluation in decreasing order of the risk factors of each assistant obtained in the surveys in order to delimit the study population; and for the correlation of the probability of suffering from ovarian cancer with these factors, the analysis was made through the statistical tool Multivariate General Linear Model. CA 125 serum levels were reached and estimated below 35 U / ml, considered as a normal reference value; It was also identified that ovarian cancer probability is higher depending on the age of the first menstrual period, firstborn age, the relationship and symptoms, considering these from 8 to 11 years of age, 0 to 5 years, according to relative aunt degree, constipation or diarrhea and loss of appetite or a very fast and continuous feeling of fullness, respectively it is concluded that showing one or more of these factors does not mean that the person will have the disease. It is recommended to encourage our society to undertake the CA 125 biomarker test as a preventive method and early ovarian cancer diagnosis through training that demonstrates relevant information.