| dc.creator | Lomonte, Bruno | |
| dc.creator | Gutiérrez, José María | |
| dc.date.accessioned | 2016-11-07T19:45:42Z | |
| dc.date.accessioned | 2022-10-19T23:36:18Z | |
| dc.date.available | 2016-11-07T19:45:42Z | |
| dc.date.available | 2022-10-19T23:36:18Z | |
| dc.date.created | 2016-11-07T19:45:42Z | |
| dc.date.issued | 1990 | |
| dc.identifier | http://www.sciencedirect.com/science/article/pii/004101019090088O | |
| dc.identifier | 0041-0101 | |
| dc.identifier | https://hdl.handle.net/10669/29160 | |
| dc.identifier | doi:10.1016/0041-0101(90)90088-O | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/4520427 | |
| dc.description.abstract | IN
A
RECENT
article
KASTURi
and
GOWDA,(1990)
described
the
dissociation
of
enzymatic
and
toxic
activities
of
phospholipases
A,
(PLA)
from
Vipera
russelli
venom
by
neutraliza-
tion
experiments
using
rabbit
polyclonal
antibodies
.
The
authors
conclude
that
their
results
"have
shown
the presence
of
distinct
sites
on
the
same
PLA
2
molecule
responsible
for
neurotoxicity,
catalytic
activity,
anticoagulant
activity
and
myotoxicity"
.
Also
they
state
that
"there
are
no
reports
explaining
the
relationship
between
the
catalytic
activity
and
pharmacological
properties
making
use of
these
(polyclonal)
antibodies",
and
"For
the
first
time
we
are
reporting
the
presence
of
multiple
pharmacological
sites
on
the
PLA
2
molecule
apart
from
the
catalytic
site
using
polyclonal
antibodies" | |
| dc.language | en_US | |
| dc.source | Toxicon 28(11):1245-7, 1990 | |
| dc.subject | Animals | |
| dc.subject | Antibodies | |
| dc.subject | Immune Sera | |
| dc.subject | Phospholipases A | |
| dc.subject | Venoms | |
| dc.subject | Immunology | |
| dc.subject | Snake venom | |
| dc.title | Dissociation of enzymatic and toxic activities by the use of antibodies | |
| dc.type | artículo científico | |
