Self-optimizing mechatronic systems react autonomously and flexibly to changing conditions. They are capable of learning and optimize their behavior throughout their life cycle. The paradigm of self-optimization is originally inspired by the behavior of biological systems. The key to the successful development of self-optimizing systems is a conceptual design process that precisely describes the desired system behavior. In the area of mechanical engineering, active principles based on physical effects such as friction or lever are widely used to concretize the construction structure and the behavior. The same approach can be found in the domain of software-engineering with software patterns such as the broker-pattern or the strategy pattern. However there is no appropriate design schema for the development of intelligent mechatronic systems covering the needs to fulfill the paradigm of self-optimization. This article proposes such a schema called Active Patterns for Self-Optimization. It is shown how a catalogue of active patterns can be derived from a set of four basic active patterns. This design approach is validated for a networked mechatronic system in a multiagent setting where the behavior is implemented according to a biologically inspired technique – the neuro-fuzzy learning method.1st IFIP International Conference on Biologically Inspired Cooperative Computing - Mechatronics and Computer ClustersRed de Universidades con Carreras en Informática (RedUNCI)