dc.creatorAmaya, Celina
dc.creatorFader Kaiser, Claudio Marcelo
dc.creatorColombo, Maria Isabel
dc.date.accessioned2018-03-27T16:05:26Z
dc.date.accessioned2022-10-15T16:26:15Z
dc.date.available2018-03-27T16:05:26Z
dc.date.available2022-10-15T16:26:15Z
dc.date.created2018-03-27T16:05:26Z
dc.date.issued2015-11
dc.identifierAmaya, Celina; Fader Kaiser, Claudio Marcelo; Colombo, Maria Isabel; Autophagy and proteins involved in vesicular trafficking; Elsevier Science; FEBS Letters; 589; 22; 11-2015; 3343-3353
dc.identifier0014-5793
dc.identifierhttp://hdl.handle.net/11336/40157
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4408965
dc.description.abstractAutophagy is an intracellular degradation system that, as a basic mechanism it delivers cytoplasmic components to the lysosomes in order to maintain adequate energy levels and cellular homeostasis. This complex cellular process is activated by low cellular nutrient levels and other stress situations such as low ATP levels, the accumulation of damaged proteins or organelles, or pathogen invasion. Autophagy as a multistep process involves vesicular transport events leading to tethering and fusion of autophagic vesicles with several intracellular compartments. This review summarizes our current understanding of the autophagic pathway with emphasis in the trafficking machinery (i.e. Rabs GTPases and SNAP receptors (SNAREs)) involved in specific steps of the pathway.
dc.languageeng
dc.publisherElsevier Science
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.febslet.2015.09.021
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0014579315008704
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAutophagosome Biogenesis
dc.subjectAutophagosome-Lysosome Fusion
dc.subjectAutophagy
dc.subjectRab Gtpase
dc.subjectSnap Receptor
dc.titleAutophagy and proteins involved in vesicular trafficking
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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