Human evolution: The non-coding revolution

dc.creatorFranchini, Lucia Florencia
dc.creatorPollard, Katherine S.
dc.date.accessioned2018-11-23T21:53:27Z
dc.date.accessioned2022-10-15T16:25:29Z
dc.date.available2018-11-23T21:53:27Z
dc.date.available2022-10-15T16:25:29Z
dc.date.created2018-11-23T21:53:27Z
dc.date.issued2017-10-02
dc.identifierFranchini, Lucia Florencia; Pollard, Katherine S.; Human evolution: The non-coding revolution; BioMed Central; Bmc Biology; 15; 1; 2-10-2017; 1-12
dc.identifier1741-7007
dc.identifierhttp://hdl.handle.net/11336/65096
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4408885
dc.description.abstractWhat made us human? Gene expression changes clearly played a significant part in human evolution, but pinpointing the causal regulatory mutations is hard. Comparative genomics enabled the identification of human accelerated regions (HARs) and other human-specific genome sequences. The major challenge in the past decade has been to link diverged sequences to uniquely human biology. This review discusses approaches to this problem, progress made at the molecular level, and prospects for moving towards genetic causes for uniquely human biology.
dc.languageeng
dc.publisherBioMed Central
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1186/s12915-017-0428-9
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-017-0428-9
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectevolution
dc.subjecthuman
dc.subjectbrain
dc.subjectprimates
dc.titleHuman evolution: The non-coding revolution
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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