Synthesis and antiviral activity of some imidazo[1,2-b][1,3,4]thiadiazole carbohydrate derivatives

dc.creatorFascio, Mirta Liliana
dc.creatorSepúlveda, Claudia Soledad
dc.creatorDamonte, Elsa Beatriz
dc.creatorD'accorso, Norma Beatriz
dc.date.accessioned2021-01-25T12:10:05Z
dc.date.accessioned2022-10-15T16:11:46Z
dc.date.available2021-01-25T12:10:05Z
dc.date.available2022-10-15T16:11:46Z
dc.date.created2021-01-25T12:10:05Z
dc.date.issued2019-07
dc.identifierFascio, Mirta Liliana; Sepúlveda, Claudia Soledad; Damonte, Elsa Beatriz; D'accorso, Norma Beatriz; Synthesis and antiviral activity of some imidazo[1,2-b][1,3,4]thiadiazole carbohydrate derivatives; Elsevier; Carbohydrate Research; 480; 7-2019; 61-66
dc.identifier0008-6215
dc.identifierhttp://hdl.handle.net/11336/123558
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4407443
dc.description.abstractHerein we describe the synthesis of imidazo[2,1-b][1,3,4]thiadiazoles from carbohydrates with D-ribo and D-xylo configuration. The antiviral activity of these compounds was tested against Junín virus (the etiological agent of Argentine hemorrhagic fever). The p-chlorophenyl derivatives showed antiviral activity in a range of micromolar concentration.
dc.languageeng
dc.publisherElsevier
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0008621519301764
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.carres.2019.05.003
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectANTIVIRAL ACTIVITY
dc.subjectD-RIBO DERIVATIVES
dc.subjectD-XILO DERIVATIVES
dc.subjectIMIDAZO[2,1-B][1,3,4]THIADIAZOLE
dc.subjectJUNÍN VIRUS
dc.titleSynthesis and antiviral activity of some imidazo[1,2-b][1,3,4]thiadiazole carbohydrate derivatives
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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