dc.creatorCortez Tornello, Pablo Roberto
dc.creatorFeresin, Gabriela Egly
dc.creatorTapia, Aníbal Alejandro
dc.creatorCuadrado, Teresita Raquel
dc.creatorAbraham, Gustavo Abel
dc.date.accessioned2020-01-02T20:35:52Z
dc.date.accessioned2022-10-15T11:29:45Z
dc.date.available2020-01-02T20:35:52Z
dc.date.available2022-10-15T11:29:45Z
dc.date.created2020-01-02T20:35:52Z
dc.date.issued2018-01
dc.identifierCortez Tornello, Pablo Roberto; Feresin, Gabriela Egly; Tapia, Aníbal Alejandro; Cuadrado, Teresita Raquel; Abraham, Gustavo Abel; Multilayered electrospun nanofibrous scaffolds for tailored controlled release of embelin; Taylor & Francis; Soft Materials; 16; 1; 1-2018; 51-61
dc.identifier1539-445X
dc.identifierhttp://hdl.handle.net/11336/93303
dc.identifier1539-4468
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4380998
dc.description.abstractPolymeric electrospun meshes are highly attractive as versatile platforms for numerous biomedical applications, tissue engineering, biosensors, and controlled release of bioactive agents. Herein, we describe the preparation and characterization of multilayered nanofibrous poly(ε-caprolactone) scaffolds with different embelin content by electrospinning technique. In vitro release in physiological and acidic pH and kinetic analysis were performed. The results show that it is possible to modulate the release profile depending on the number and thickness of layers added to drug-loaded scaffold that acts as an embelin reservoir. Electrospun multilayered scaffolds present characteristics, morphology and release profiles that could be very attractive for use as embelin controlled release systems.
dc.languageeng
dc.publisherTaylor & Francis
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/doi/full/10.1080/1539445X.2017.1398173
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1080/1539445X.2017.1398173
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectDRUG RELEASE
dc.subjectELECTROSPINNING
dc.subjectEMBELIN
dc.subjectMULTILAYERED SCAFFOLDS
dc.subjectNANOFIBERS
dc.titleMultilayered electrospun nanofibrous scaffolds for tailored controlled release of embelin
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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