Thermoresponsive behavior of scaffolds based on fumarate-N-isopropylacrylamide copolymers for potential biomedical applications

dc.creatorBravi Costantino, Maria Leticia
dc.creatorOberti, Tamara Gisela
dc.creatorCortizo, Ana María
dc.creatorCortizo, Maria Susana
dc.date.accessioned2022-09-27T17:57:26Z
dc.date.accessioned2022-10-15T10:46:27Z
dc.date.available2022-09-27T17:57:26Z
dc.date.available2022-10-15T10:46:27Z
dc.date.created2022-09-27T17:57:26Z
dc.date.issued2021-06
dc.identifierBravi Costantino, Maria Leticia; Oberti, Tamara Gisela; Cortizo, Ana María; Cortizo, Maria Susana; Thermoresponsive behavior of scaffolds based on fumarate-N-isopropylacrylamide copolymers for potential biomedical applications; Taylor & Francis As; International Journal Of Polymeric Materials; 71; 12; 6-2021; 923-931
dc.identifier0091-4037
dc.identifierhttp://hdl.handle.net/11336/170668
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4377217
dc.description.abstractIn this work, we analyze the thermoresponsive behavior of scaffolds prepared from dioctyl fumarate-N-isopropylacrylamide copolymers (DFN) with different compositions. Lower critical solution temperature (LCST) of these biomaterials was determined by differential scanning calorimetry (DSC) and transmittance measurement, finding that LCST increase when the content of fumaric monomer increase in the copolymer. The effect of this behavior on the swelling capacity, superficial hydrophilicity and cellular response was also studied. Our results show that both cell viability and osteoblastic cell differentiation are regulated not only by the composition of the copolymer, but also the LCST of each one of them.
dc.languageeng
dc.publisherTaylor & Francis As
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1080/00914037.2021.1931206
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectBIOCOMPATIBLE POLYMERS
dc.subjectFUMARIC COPOLYMERS
dc.subjectLOW CRITICAL SOLUTION TEMPERATURE
dc.subjectSCAFFOLDS
dc.subjectTHERMORESPONSIVE POLYMER
dc.titleThermoresponsive behavior of scaffolds based on fumarate-N-isopropylacrylamide copolymers for potential biomedical applications
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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