dc.creator | Hare, Jonathan | |
dc.creator | Morrison, David | |
dc.creator | Nielsen, Morten | |
dc.date.accessioned | 2021-07-07T01:39:33Z | |
dc.date.accessioned | 2022-10-15T07:18:14Z | |
dc.date.available | 2021-07-07T01:39:33Z | |
dc.date.available | 2022-10-15T07:18:14Z | |
dc.date.created | 2021-07-07T01:39:33Z | |
dc.date.issued | 2021-02-19 | |
dc.identifier | Hare, Jonathan; Morrison, David; Nielsen, Morten; Sampling SARS-CoV-2 Proteomes for Predicted CD8 T-Cell Epitopes as a Tool for Understanding Immunogenic Breadth and Rational Vaccine Design; Frontiers in Bioscience; Frontiers in Bioinformatics; 1; 622992; 19-2-2021; 1-5 | |
dc.identifier | http://hdl.handle.net/11336/135604 | |
dc.identifier | 2673-7647 | |
dc.identifier | CONICET Digital | |
dc.identifier | CONICET | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/4359562 | |
dc.description.abstract | Predictive models for vaccine design have become a powerful and necessary resource for the expeditiousness design of vaccines to combat the ongoing SARS-CoV-2 global pandemic. Here we use the power of these predicted models to assess the sequence diversity of circulating SARS-CoV-2 proteomes in the context of an individual?s CD8 T-cell immune repertoire to identify potential. defined regions of immunogenicity. Using this approach of expedited and rational CD8 T-cell vaccine design, it may be possible to develop a therapeutic vaccine candidate with the potential for both global and local coverage. | |
dc.language | eng | |
dc.publisher | Frontiers in Bioscience | |
dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fbinf.2021.622992/full | |
dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3389/fbinf.2021.622992 | |
dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Sars-Cov-2 | |
dc.subject | Epitopes | |
dc.subject | T cell | |
dc.subject | COVID-19 | |
dc.title | Sampling SARS-CoV-2 Proteomes for Predicted CD8 T-Cell Epitopes as a Tool for Understanding Immunogenic Breadth and Rational Vaccine Design | |
dc.type | info:eu-repo/semantics/article | |
dc.type | info:ar-repo/semantics/artículo | |
dc.type | info:eu-repo/semantics/publishedVersion | |