Synthesis of C-C bonded dimeric steroids by olefin metathesis

dc.creatorEdelsztein, Valeria Carolina
dc.creatorDi Chenna, Pablo Hector
dc.creatorBurton, Gerardo
dc.date.accessioned2019-03-06T20:10:56Z
dc.date.accessioned2022-10-15T05:42:13Z
dc.date.available2019-03-06T20:10:56Z
dc.date.available2022-10-15T05:42:13Z
dc.date.created2019-03-06T20:10:56Z
dc.date.issued2009-05
dc.identifierEdelsztein, Valeria Carolina; Di Chenna, Pablo Hector; Burton, Gerardo; Synthesis of C-C bonded dimeric steroids by olefin metathesis; Pergamon-Elsevier Science Ltd; Tetrahedron; 65; 18; 5-2009; 3615-3623
dc.identifier0040-4020
dc.identifierhttp://hdl.handle.net/11336/71110
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4351049
dc.description.abstractFive new C-C bonded steroidal homodimers derived from deoxycholic acid, pregnenolone, and progesterone were synthesized by an olefin metathesis reaction assisted by microwave heating. Microwave improved the yield and accelerated the reaction allowing the use of less catalyst with good results (2.5 mol %). Due to the bulky nature of the steroidal skeleton the more favorable E-dimers were formed as the sole or major products depending on the linker length. © 2009 Elsevier Ltd. All rights reserved.
dc.languageeng
dc.publisherPergamon-Elsevier Science Ltd
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0040402009003603
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1016/j.tet.2009.03.006
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDIMERIC STEROIDS
dc.subjectDIMERIZATION
dc.subjectMETATHESIS
dc.subjectMICROWAVE
dc.titleSynthesis of C-C bonded dimeric steroids by olefin metathesis
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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