dc.creatorTittarelli, Estefanía
dc.creatorBarrero, Paola Roxana
dc.creatorMistchenko, Alicia Susana
dc.creatorValinotto, Laura Elena
dc.date.accessioned2020-01-14T17:47:34Z
dc.date.accessioned2022-10-15T05:28:05Z
dc.date.available2020-01-14T17:47:34Z
dc.date.available2022-10-15T05:28:05Z
dc.date.created2020-01-14T17:47:34Z
dc.date.issued2016-01
dc.identifierTittarelli, Estefanía; Barrero, Paola Roxana; Mistchenko, Alicia Susana; Valinotto, Laura Elena; Secondary dengue virus infections during the 2009 outbreak in Buenos Aires; Wiley Blackwell Publishing, Inc; Tropical Medicine And International Health; 21; 1; 1-2016; 28-32
dc.identifier1360-2276
dc.identifierhttp://hdl.handle.net/11336/94619
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4349735
dc.description.abstractObjectives: To evaluate the occurrence of secondary dengue virus (DENV) infections during the 2009 outbreak in a non-endemic area. Viral loads were evaluated in serum from acute-phase patients, comparing primary and secondary infection. Methods: Serum samples from patients with clinical diagnosis of suspected dengue were referred to the Virology Laboratory at 'Ricardo Gutiérrez' Children's Hospital. Dengue-positive samples were classified as primary or secondary DENV infections through serological methods (anti-DENV IgM and IgG). Viral loads were measured by quantitative real-time PCR (qRT-PCR) in samples obtained in the first 5 days of infection. Statistical analyses were performed to evaluate factors that might correlate with differences in the viral load of primary or secondary infection. Results: A total of 229 DENV cases were confirmed; among them, 22.7% were secondary infections. No significant differences were found between the viral load of primary and secondary infections. Conclusion: We detected a high percentage of secondary DENV infections in a non-endemic area; this finding might correspond to socio-demographic characteristics of the group under study or indicate a previous cryptic DENV circulation causing inapparent infections.
dc.languageeng
dc.publisherWiley Blackwell Publishing, Inc
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/full/10.1111/tmi.12619
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1111/tmi.12619
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectDENGUE VIRUS
dc.subjectSECONDARY INFECTIONS
dc.subjectVIRAL LOAD
dc.titleSecondary dengue virus infections during the 2009 outbreak in Buenos Aires
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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