Progesterone receptors in normal breast development and breast cancer

dc.creatorGiulianelli, Sebastian Jesus
dc.creatorLamb, Caroline Ana
dc.creatorLanari, Claudia Lee Malvina
dc.date.accessioned2021-09-09T17:47:11Z
dc.date.accessioned2022-10-15T03:23:33Z
dc.date.available2021-09-09T17:47:11Z
dc.date.available2022-10-15T03:23:33Z
dc.date.created2021-09-09T17:47:11Z
dc.date.issued2021-06
dc.identifierGiulianelli, Sebastian Jesus; Lamb, Caroline Ana; Lanari, Claudia Lee Malvina; Progesterone receptors in normal breast development and breast cancer; Portland Press; Essays In Biochemistry; 6-2021
dc.identifier0071-1365
dc.identifierhttp://hdl.handle.net/11336/140025
dc.identifier1744-1358
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4339709
dc.description.abstractProgesterone receptors (PR) play a pivotal role in many female reproductive tissues such as the uterus, the ovary, and the mammary gland (MG). Moreover, PR play a key role in breast cancer growth and progression. This has led to the development and study of different progestins and antiprogestins, many of which are currently being tested in clinical trials for cancer treatment. Recent reviews have addressed the role of PR in MG development, carcinogenesis, and breast cancer growth. Thus, in this review, in addition to making an overview on PR action in normal and tumor breast, the focus has been put on highlighting the still unresolved topics on hormone treatment involving PR isoforms and breast cancer prognosis.
dc.languageeng
dc.publisherPortland Press
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://portlandpress.com/essaysbiochem/article/doi/10.1042/EBC20200163/228842/Progesterone-receptors-in-normal-breast
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1042/EBC20200163
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBREAST CANCER
dc.subjectPROGESTERONE RECEPTORS
dc.subjectNORMAL BREAST
dc.subjectPROGESTINS
dc.subjectANTIPROGESTINS
dc.subjectENDOCRINE THERAPIES
dc.titleProgesterone receptors in normal breast development and breast cancer
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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