Mechanisms involved in the expansion of Tregs during pregnancy: Role of IL-2/STAT5 signalling

dc.creatorArruvito, Maria Lourdes
dc.creatorFainboim, Leonardo
dc.date.accessioned2019-01-07T20:20:38Z
dc.date.accessioned2022-10-15T03:11:32Z
dc.date.available2019-01-07T20:20:38Z
dc.date.available2022-10-15T03:11:32Z
dc.date.created2019-01-07T20:20:38Z
dc.date.issued2011-03
dc.identifierArruvito, Maria Lourdes; Fainboim, Leonardo; Mechanisms involved in the expansion of Tregs during pregnancy: Role of IL-2/STAT5 signalling; Elsevier Ireland; Journal of Reproductive Immunology; 88; 2; 3-2011; 93-98
dc.identifier0165-0378
dc.identifierhttp://hdl.handle.net/11336/67626
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4338655
dc.description.abstractSeveral studies have reported that the fine-tuning of regulatory T cells (Tregs) is required for a successful pregnancy and for the control of autoimmune diseases. Here, we review the mechanisms that control the expansion of Tregs, based on insights obtained from the study of women suffering unsuccessful pregnancies and on recent data from patients with autoimmune diseases or with chronic viral infections such as HCV. In particular, we review the role of endocrine factors and IL-2/STAT5 signalling in the impaired expansion of Tregs.
dc.languageeng
dc.publisherElsevier Ireland
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1016/j.jri.2010.12.007
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0165037811000064
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectHUMAN REPRODUCTION
dc.subjectIL-2
dc.subjectREGULATORY T CELL
dc.subjectSTAT-5
dc.titleMechanisms involved in the expansion of Tregs during pregnancy: Role of IL-2/STAT5 signalling
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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