dc.creatorDi Leo Lira, Paola Maria del Rosario
dc.creatorRetta, Daiana Sabrina
dc.creatorVan Baren, Catalina Maria
dc.creatorGorzalczany, Susana Beatriz
dc.creatorBandoni, Arnaldo Luis
dc.date.accessioned2019-01-07T20:30:20Z
dc.date.accessioned2022-10-14T23:47:04Z
dc.date.available2019-01-07T20:30:20Z
dc.date.available2022-10-14T23:47:04Z
dc.date.created2019-01-07T20:30:20Z
dc.date.issued2010-09
dc.identifierDi Leo Lira, Paola Maria del Rosario; Retta, Daiana Sabrina; Van Baren, Catalina Maria; Gorzalczany, Susana Beatriz; Bandoni, Arnaldo Luis; Phytochemical variability of populations of Aloysia citriodora from Argentina; Georg Thieme Verlag Kg; Planta Medica; 76; 12; 9-2010
dc.identifier0032-0943
dc.identifierhttp://hdl.handle.net/11336/67629
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4321104
dc.description.abstractAloysia citriodora Palau (Verbenaceae) is one of the most widely used herbs in the Argentine traditional medicine as antispasmodic, sedative and for the treatment of stomachache. Its worldwide use has promoted its cultivation not only in our country but also in several Latin American countries, Europe and Asia. There are official monographs in Argentine (FA) and European Pharmacopoeias (PhEU, as „lemon verbena) for the pharmaceutical quality control. Our working group is devoted to update the respective monograph of the FA, taking in account the detected phytochemical variability of local populations. Parameters for a quality profile of volatile metabolites were previously established [1,2]. At this time we have evaluated the phytochemical variability of several populations using the technique by the European Pharmacopoeia (HPLC), in order to identify the best materials for crops affordable for the pharmaceutical industry. We analyzed 22 populations from 12 regions from Argentina, both in culture and wild materials. Our results show significant differences in the contents of verbascoside: from 0.5 to 4.8%, being 2.5% the minimum accepted value in the PhEu. Other peaks were detected in the HPLC profiles, some of them with similar UV spectra as verbascoside, meanwhile others with polyphenolic UV pattern. Therefore, in vitro assays will be undertaken to determine if the quantity of verbascoside itself affects proportionally the pharmacological activity
dc.languageeng
dc.publisherGeorg Thieme Verlag Kg
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1055/s-0030-1264347
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0030-1264347
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectAloysia citriodora
dc.subjectessential oil
dc.subjectCholeretic activity
dc.subjectAntispasmodic activity
dc.titlePhytochemical variability of populations of Aloysia citriodora from Argentina
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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