Highly stereoselective synthesis of steroidal 2,5-diketopiperazines based on isocyanide chemistry

dc.creatorBruttomesso, Andrea
dc.creatorEiras, Javier
dc.creatorRamirez, Javier Alberto
dc.creatorGalagovsky, Lydia Raquel
dc.date.accessioned2019-03-06T20:10:42Z
dc.date.accessioned2022-10-14T23:46:54Z
dc.date.available2019-03-06T20:10:42Z
dc.date.available2022-10-14T23:46:54Z
dc.date.created2019-03-06T20:10:42Z
dc.date.issued2009-07
dc.identifierBruttomesso, Andrea; Eiras, Javier; Ramirez, Javier Alberto; Galagovsky, Lydia Raquel; Highly stereoselective synthesis of steroidal 2,5-diketopiperazines based on isocyanide chemistry; Pergamon-Elsevier Science Ltd; Tetrahedron Letters; 50; 28; 7-2009; 4022-4024
dc.identifier0040-4039
dc.identifierhttp://hdl.handle.net/11336/71109
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4321084
dc.description.abstractIn this Letter we report that the Ugi reaction/cyclization sequence on a steroidal 17-carboxaldehyde leads to novel steroidal 2,5-diketopiperazines with a noteworthy stereoselectivity. A wide variety in the substitution pattern in the heterocyclic moiety was easily achieved by changing the components in the Ugi reaction. © 2009 Elsevier Ltd. All rights reserved.
dc.languageeng
dc.publisherPergamon-Elsevier Science Ltd
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1016/j.tetlet.2009.03.219
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0040403909007886
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject2,5-DIKETOPIPERAZINES
dc.subjectHETEROCYCLIC STEROIDS
dc.subjectMULTICOMPONENT REACTION
dc.subjectUGI REACTION
dc.titleHighly stereoselective synthesis of steroidal 2,5-diketopiperazines based on isocyanide chemistry
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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