Drug Transporters

dc.contributorTalevi, Alan
dc.contributorQuiroga, Pablo Alejandro Mauricio
dc.creatorTalevi, Alan
dc.creatorBellera, Carolina Leticia
dc.creatorPesce, Guido Oscar
dc.date.accessioned2021-08-02T15:23:33Z
dc.date.accessioned2022-10-14T23:39:58Z
dc.date.available2021-08-02T15:23:33Z
dc.date.available2022-10-14T23:39:58Z
dc.date.created2021-08-02T15:23:33Z
dc.date.issued2018
dc.identifierTalevi, Alan; Bellera, Carolina Leticia; Pesce, Guido Oscar; Drug Transporters; Springer Nature Switzerland AG; 2018; 331-348
dc.identifier978-3-319-99593-9
dc.identifierhttp://hdl.handle.net/11336/137585
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/4320485
dc.description.abstractMembrane transporters perform a central function in many essential body functions, including traffic and compartmentalization of physiologic compounds, absorption of physiologic compounds (and, occasionally, structurally related xenobiotics, including drugs), and protection from potentially toxic exogenous compounds, which includes limiting their absorption and/or distribution and promoting their elimination (with no chemical modifications or as metabolites). The impact of drug biotransformation enzymes on pharmacokinetics and clinical outcome is much better understood than that of drug transporters, possibly due to the earlier discovery of metabolizing enzymes. The science of drug transporters can still be described as an emerging field, with knowledge on their structure, function, and regulation being continuously expanded.
dc.languageeng
dc.publisherSpringer Nature Switzerland AG
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://link.springer.com/chapter/10.1007/978-3-319-99593-9_14
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1007/978-3-319-99593-9_14
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.sourceADME Processes in Pharmaceutical Sciences: Dosage, Design, and Pharmacotherapy Success
dc.subjectABC TRANSPORTERS
dc.subjectATP-BINDING CASSETTE TRANSPORTERS
dc.subjectCROSS RESISTANCE
dc.subjectDRUG ELIMINATION
dc.subjectDRUG TRANSPORTERS
dc.subjectEFFLUX TRANSPORTERS
dc.subjectELIMINATION
dc.subjectKIDNEY
dc.subjectLIVER
dc.subjectMDR1
dc.subjectMRP
dc.subjectMULTI-DRUG RESISTANCE
dc.subjectMULTI-DRUG RESISTANCE ASSOCIATED PROTEINS
dc.subjectP-GLYCOPROTEIN
dc.subjectP-GP
dc.subjectORGANIC ANION TRANSPORTERS
dc.subjectSLC TRANSPORTERS
dc.subjectSOLUTE CARRIER TRANSPORTERS
dc.titleDrug Transporters
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typeinfo:eu-repo/semantics/bookPart
dc.typeinfo:ar-repo/semantics/parte de libro


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