| dc.contributor | Bizarri, Mariano | |
| dc.creator | Alberca, Lucas Nicolás | |
| dc.creator | Talevi, Alan | |
| dc.date.accessioned | 2021-11-11T22:03:22Z | |
| dc.date.accessioned | 2022-10-14T21:54:56Z | |
| dc.date.available | 2021-11-11T22:03:22Z | |
| dc.date.available | 2022-10-14T21:54:56Z | |
| dc.date.created | 2021-11-11T22:03:22Z | |
| dc.date.issued | 2020 | |
| dc.identifier | Alberca, Lucas Nicolás; Talevi, Alan; The efficiency of multi-target drugs: A network approach; Springer; 2020; 63-75 | |
| dc.identifier | 978-3-030-32856-6 | |
| dc.identifier | 2661-8923 | |
| dc.identifier | http://hdl.handle.net/11336/146760 | |
| dc.identifier | 2661-8915 | |
| dc.identifier | CONICET Digital | |
| dc.identifier | CONICET | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/4310990 | |
| dc.description.abstract | Multi-target agents have attracted great attention in the last 15 years, as they are expected to provide more efficacious and safer therapeutic solutions, less prone to drug resistance phenomena. They thus seem particularly valuable in the fields of complex disorders and infectious diseases. We discuss the generalities of tailored multi-target drug design, including target combination choice, optimization of potency ratio to the different targets, peculiarities of computer-guided drug discovery and design considerations. | |
| dc.language | eng | |
| dc.publisher | Springer | |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/book/10.1007/978-3-030-32857-3#about | |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1007/978-3-030-32857-3_3 | |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.source | Approaching complex diseases | |
| dc.subject | MULTI-TARGET DRUG | |
| dc.subject | NETWORK PHARMACOLOGY | |
| dc.subject | SYSTEMS BIOLOGY | |
| dc.subject | NETWORKS | |
| dc.subject | COMPLEX DISORDERS | |
| dc.subject | COMPLEX DISEASES | |
| dc.subject | DRUG DISCOVERY | |
| dc.title | The efficiency of multi-target drugs: A network approach | |
| dc.type | info:eu-repo/semantics/publishedVersion | |
| dc.type | info:eu-repo/semantics/bookPart | |
| dc.type | info:ar-repo/semantics/parte de libro | |
