dc.creatorAlmeida, Juliana S.
dc.creatorJezur, Luciane
dc.creatorFontana, Marcia C.
dc.creatorPaese, Karina
dc.creatorSilva, Cristiane B.
dc.creatorPohlmann, Adriana Raffin
dc.creatorGuterres, Sílvia Stanisçuaski
dc.creatorBeck, Ruy Carlos Ruver
dc.date2009-06-22T03:00:00Z
dc.date2009
dc.date.accessioned2017-03-08T20:12:27Z
dc.date.available2017-03-08T20:12:27Z
dc.identifierhttp://hdl.handle.net/10915/7742
dc.identifierhttp://www.latamjpharm.org/trabajos/28/2/LAJOP_28_2_1_1_599ZY133S8.pdf
dc.identifierhttp://sedici.unlp.edu.ar/handle/10915/7742
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/429809
dc.descriptionThe use of two alternative vegetable oils (grape seed oil and almond kernel oil) to prepare nanoparticulated delivery systems (nanocapsules and nanoemulsions) for active substances was evaluated. They were prepared by interfacial deposition of preformed polymer (poly-ε-caprolactone) or spontaneous emulsification, respectively. All formulations presented nanometric size, polydispersity index below 0.30, negative zeta potential and spherical-shaped particles. Benzophenone-3, as a model substance was efficiently entrapped in these systems, independent on the type of oily phase. Its association did not alter significantly the physicochemical properties of the nanoparticle dispersions, which remained adequate until 6 months of storage. Nanocapsules and nanoemulsions prepared with both vegetable oils were suitable to delay benzophenone-3 photodegradation under UV radiation.
dc.languageen
dc.relationLatin American Journal of Pharmacy
dc.relationvol. 28, no. 2
dc.subjectalmond kernel oil; grape seed oil; nanoparticles
dc.subjectFarmacia
dc.subjectPreparaciones Farmacéuticas
dc.subjectaceite vegetal
dc.titleOil-based nanoparticles containing alternative vegetable oils (grape seed oil and almond kernel oil): preparation and characterization
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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