Gastroduodenal lesions in children with juvenile rheumatoid arthritis

dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.creatorLen, Claudio Arnaldo [UNIFESP]
dc.creatorHilário, Maria Odete Esteves [UNIFESP]
dc.creatorKawakami, Elisabete [UNIFESP]
dc.creatorTerreri, Maria Teresa Ramos Ascensão [UNIFESP]
dc.creatorBecker, D. J.
dc.creatorGoldenberg, José [UNIFESP]
dc.creatorFagundes Neto, Ulysses [UNIFESP]
dc.date.accessioned2018-06-15T17:30:26Z
dc.date.accessioned2022-10-07T21:26:15Z
dc.date.available2018-06-15T17:30:26Z
dc.date.available2022-10-07T21:26:15Z
dc.date.created2018-06-15T17:30:26Z
dc.date.issued1999-03-01
dc.identifierHepato-gastroenterology. Athens: H G E Update Medical Publ Ltd., v. 46, n. 26, p. 991-996, 1999.
dc.identifier0172-6390
dc.identifierhttp://repositorio.unifesp.br/11600/43775
dc.identifierWOS:000080360400067
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/4029324
dc.description.abstractBACKGROUND/AIMS: There are few studies about gastrointestinal abnormalities in patients with juvenile rheumatoid arthritis - probably due to the fact that this association is not frequently recognized. The aim of our study was to observe the prevalence of endoscopic gastroduodenal lesions in these patients.METHODOLOGY: Fourteen patients with juvenile rheumatoid arthritis, all of them using non-steroidal anti-inflammatory drugs associated or not with methotrexate, were assessed clinically and by endoscopy. Gastric antrum biopsy and Helicobacter pylori search were also performed.RESULTS: The mean age of the patients was 10.6 years (7 boys). Abdominal pain was observed in 27% of them. Macroscopic endoscopic lesions were found in 43% and infection by Helicobacter pylori in 57%. The correlation between anemia and endoscopic abnormalities was statistically significant (p<0.05).CONCLUSIONS: Our data show that patients with juvenile rheumatoid arthritis have considerable susceptibility to gastroduodenal lesions, especially if they are using any drug association and present anemia.
dc.languageeng
dc.publisherH G E Update Medical Publ Ltd.
dc.relationHepato-gastroenterology
dc.rightsAcesso restrito
dc.subjectjuvenile rheumatoid arthritis
dc.subjectnon-steroidal anti-inflammatory drugs
dc.subjectgastropathy
dc.titleGastroduodenal lesions in children with juvenile rheumatoid arthritis
dc.typeArtigo


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