Estrogen therapy reduces nocturnal periodic limb movements

dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.creatorHachul, Helena
dc.creatorBaracat, Edmund Chada [UNIFESP]
dc.creatorSoares, Jose Maria [UNIFESP]
dc.creatorHaidar, Mauro Abi [UNIFESP]
dc.creatorMello, Marco Tulio de [UNIFESP]
dc.creatorTufik, Sergio [UNIFESP]
dc.creatorBittencourt, Lia Rita Azeredo [UNIFESP]
dc.date.accessioned2016-01-24T13:49:13Z
dc.date.accessioned2022-10-07T21:25:06Z
dc.date.available2016-01-24T13:49:13Z
dc.date.available2022-10-07T21:25:06Z
dc.date.created2016-01-24T13:49:13Z
dc.date.issued2007-11-20
dc.identifierMaturitas. Clare: Elsevier B.V., v. 58, n. 3, p. 319-322, 2007.
dc.identifier0378-5122
dc.identifierhttp://repositorio.unifesp.br/handle/11600/30152
dc.identifier10.1016/j.maturitas.2007.08.009
dc.identifierWOS:000251541200013
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/4029226
dc.description.abstractIt is believed that periodic lirnb movement (PLM) and more specifically, restless leg syndrome (RLS), are a common cause of insomnia. and one study in the literature examined PLM when associated to the use of estrogens. Polo-Kantola et al. [Polo-Kantola P, Rauhala E, Erkkola R, Irjala K, Polo O. Estrogen replacement therapy and nocturnal periodic limb movements: a randomized controlled trial. Obstet Gynecol 2001;97(4):548-54] observed that estrogen therapy improved subjective sleep quality regardless of periodic limb movements or related arousals. Herein is a case of a symptomatic postmenopausal patient with high PLM index who complained of insomnia and leg pain. Given that the patient had hot flashes and a high Kupperman Menopausal Index (which evaluates climacteric symptoms), we decided to administer transdermal ESTRADOT 25 mu g (Novartis, Brazil) twice-a-week. Our patient experienced a significant decrease in PLM as well as a great increase in REM and a slight increase in slow wave sleep (stages 3 and 4), as shown in the polysomnography. the patient reported an overall improvement in her condition. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
dc.languageeng
dc.publisherElsevier B.V.
dc.relationMaturitas
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.rightsAcesso aberto
dc.subjectperiodic leg movements
dc.subjectmenopause
dc.subjectestrogen therapy
dc.subjectsleep
dc.subjectsleep disturbances
dc.titleEstrogen therapy reduces nocturnal periodic limb movements
dc.typeArtigo


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