Gastric emptying evaluation in children with erosive gastroesophageal reflux disease

dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.creatorMachado, Rodrigo Strehl [UNIFESP]
dc.creatorYamamoto, Erica [UNIFESP]
dc.creatorSilva Patricio, Francy Reis da [UNIFESP]
dc.creatorReber, Marialice [UNIFESP]
dc.creatorKawakami, Elisabete [UNIFESP]
dc.date.accessioned2016-01-24T13:59:38Z
dc.date.accessioned2022-10-07T21:23:16Z
dc.date.available2016-01-24T13:59:38Z
dc.date.available2022-10-07T21:23:16Z
dc.date.created2016-01-24T13:59:38Z
dc.date.issued2010-05-01
dc.identifierPediatric Surgery International. New York: Springer, v. 26, n. 5, p. 473-478, 2010.
dc.identifier0179-0358
dc.identifierhttp://repositorio.unifesp.br/handle/11600/32502
dc.identifier10.1007/s00383-010-2579-4
dc.identifierWOS:000276885300004
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/4029061
dc.description.abstractDelayed gastric emptying may be an important contributing factor to gastroesophageal reflux disease (GERD) in children, but there are limited data on its evaluation in children with erosive-GERD. This study aims to evaluate the gastric emptying of a solid meal in patients with erosive-GERD.Nineteen patients (age range 8.79-17.9 years) with erosive esophagitis and 14 healthy controls (age range from 8.04 to 18.7 years) were compared. Esophagitis was graded according to Los Angeles classification. the gastric emptying was evaluated by (13)C-octanoic breath test, which was performed after a 344 kcal standardized solid test meal. Symptoms were evaluated using a standardized questionnaire.The two most prevalent symptoms were nausea and epigastric pain, which were reported by 12 (63.2%) patients. Irritable bowel syndrome was present in 26.3% (5/19). the median gastric emptying half-time in patients was 160 min (interquartile range [IQR] 140-174 min), which was not different from the controls' figure (median 157 min, IQR 143-170 min). Additionally, the lag time and the gastric emptying coefficient were not significantly different between the study groups.Delayed gastric emptying is not associated with erosive esophagitis in children with GERD, when compared to controls.
dc.languageeng
dc.publisherSpringer
dc.relationPediatric Surgery International
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.rightsAcesso restrito
dc.subjectEsophagitis
dc.subjectPeptic
dc.subjectGastric emptying
dc.subjectOctanoic acids
dc.titleGastric emptying evaluation in children with erosive gastroesophageal reflux disease
dc.typeArtigo


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