Artigo
Twenty-five years of HTLV type II follow-up with a possible case of tropical spastic paraparesis in the Kayapo, a Brazilian Indian tribe
Fecha
1996-11-20Registro en:
Aids Research and Human Retroviruses. New Rochelle: Mary Ann Liebert Inc, v. 12, n. 17, p. 1623-1627, 1996.
0889-2229
10.1089/aid.1996.12.1623
WOS:A1996VV29200007
Autor
Black, F. L.
Biggar, R. J.
Lal, R. B.
Gabbai, Alberto Alain [UNIFESP]
Vieira, JPB
Institución
Resumen
A longitudinal study, spanning 25 years and great demographic and cultural change, found a persistently high prevalence of human T-lymphotropic virus type II (HTLV-II) in the Xikrin Kayapo Indians of Brazil, More than 10% of the children continue to develop immune reactions to the virus in infancy, a sharp increase in seroprevalence occurs between ages 15 and 30 years, and prevalence in older women still approaches 100%, This suggests that the major modes of transmission (breast milk and sexual activity) have not changed, the demonstration of stable maintenance of HTLV-II in one ethnic group makes migration theories of its dispersal more plausible, However, the infection may not be a negligible burden on population survival: at least 1 of 62 persons followed until age 40 years died of possible tropical spastic paraparesis (TSP).